Current Diabetes Reports

, Volume 6, Issue 6, pp 431–438 | Cite as

Central nervous system involvement in diabetes mellitus

  • Dinesh Selvarajah
  • Solomon TesfayeEmail author


Diabetic complications result in much morbidity and mortality and considerable consumption of scarce medical resources. Thus, elucidation of the risk factors and pathophysiologic mechanisms underlying diabetic complications is important. The effects of diabetes on the central nervous system (CNS) result in cognitive dysfunction and cerebrovascular disease. Treatmentrelated hypoglycemia also has CNS consequences. Advances in neuroimaging now provide greater insights into the structural and functional impact of diabetes on the CNS. Greater understanding of CNS involvement could lead to new strategies to prevent or reverse the damage caused by diabetes mellitus.


Hypoglycemia Diabetic Neuropathy Central Nervous System Involvement Diabetic Peripheral Neuropathy Hypoglycemic Coma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Current Science Inc 2006

Authors and Affiliations

  1. 1.Diabetes Research UnitRoyal Hallamshire HospitalSheffieldUK

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