Current Diabetes Reports

, Volume 4, Issue 3, pp 194–198 | Cite as

Association of diabetes and hepatitis C infection: Epidemiologic evidence and pathophysiologic insights

  • Gül Bahtiyar
  • John J. Shin
  • Ayse Aytaman
  • James R. Sowers
  • Samy I. McFarlane


Up to one third of patients with chronic hepatitis C virus (HCV) develop type 2 diabetes mellitus (DM). This prevalence is much higher than that observed in the general population, and in patients with other chronic liver diseases such as hepatitis B virus, alcoholic liver disease, and primary biliary cirrhosis. Further, HCV seropositivity in patients with DM appears to be higher than in the general population. Postliver transplantation DM also appears to be higher among patients with HCV. In this article, we review the epidemiologic association between HCV and DM, highlighting the most recent pathophysiologic insights into the mechanisms underlying this association.


Chronic Hepatitis NASH Primary Biliary Cirrhosis Alcoholic Liver Disease Nonalcoholic Fatty Liver Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Current Science Inc. 2004

Authors and Affiliations

  • Gül Bahtiyar
  • John J. Shin
  • Ayse Aytaman
  • James R. Sowers
  • Samy I. McFarlane
    • 1
  1. 1.Division of Endocrinology, Diabetes and HypertensionSUNY-Downstate Health Science CenterBrooklynUSA

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