How to Best Image Colorectal Liver Metastases

  • G.A. ZamboniEmail author
  • A. Mazzaro
  • G. Mansueto
Diagnostic and Interventional Radiology Innovations in Colorectal Cancer (S Gourtsoyianni, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Diagnostic and Interventional Radiology Innovations in Colorectal Cancer


Purpose of Review

Colorectal liver metastases affect about half of the patients with colorectal cancer and have an impact on prognosis. Resection of liver metastases, even after downstaging with chemotherapy, improves patient survival. Several imaging modalities are available for initial detection and follow-up of liver metastases. Our purpose is to review the advantages and disadvantages of each modality and to determine which is the optimal way to evaluate colorectal liver metastases in each phase of the patient’s journey.

Recent Findings

The available evidence derives mostly from comparative studies and meta-analysis, with only few available randomized trials. MRI with DWI sequences and liver-specific contrast agents appears to be the most accurate modality for the detection of liver metastases.


Different imaging modalities can be used successfully for the detection and follow-up of colorectal liver metastases, depending on the stage of the disease and patient characteristics. A stepwise approach is recommended, instead of using all modalities in each patient.


Colon cancer Liver metastases Liver resection Chemotherapy follow-up 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


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© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.UOC Radiologia BRAzienda Ospedaliera Universitaria Integrata di VeronaVeronaItaly

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