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Current Colorectal Cancer Reports

, Volume 9, Issue 2, pp 136–145 | Cite as

MRI-Based Assessment of Tumor Regression in Rectal Cancer

  • Uday B. Patel
  • Gina BrownEmail author
Localized Rectal Cancer (R Glynne-Jones, Section Editor)
  • 235 Downloads

Abstract

Until recently, there has been uncertainty regarding the exact role, importance, and validity of MRI in restaging rectal cancers after preoperative treatment. MRI tumor reassessment has wide-ranging implications, for example, altering surgical planning, timing of surgery, and potential deferral of surgery for MRI-identified good responders. Several approaches for restaging rectal cancer after treatment have been proposed, for example, T staging, volume reduction of tumor, MRI tumor regression grading, and diffusion-weighted-imaging assessment. Likewise several approaches to restaging the potential resection margin and nodal disease have also been investigated. This article seeks to review the evidence for each of the proposed approaches to restage rectal cancer after chemoradiotherapy and concludes with recommendations for current clinical practice.

Keywords

Rectal cancer MRI Chemoradiotherapy Volume Diffusion Tumor regression grade 

Notes

Acknowledgment

This authors are supported by a grant from the National Institute for Health Research (UK).

Conflict of Interest

Uday B. Patel declares he has no conflict of interest.

Gina Brown declares she has no conflict of interest.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of RadiologyThe Royal Marsden Hospital NHS TrustSuttonUK

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