Should There Be Gender Differences in the Guidelines for Colorectal Cancer Screening?
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Colorectal cancer screening guidelines are identical for men and women despite reported differences in epidemiology, endoscopy performance, screening preferences, and screening uptake. High-quality research is needed to determine whether gender aspects may in real world increase acceptance and overcome screening barriers, which may lead to better use of limited resources allocated for public health.
KeywordsColorectal cancer Screening Gender Prevention and early detection
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- 3.Segnan N, Patnick J, von Karsa L, editors. European Guidelines for quality assurance in colorectal cancer screening and diagnosis. 1st ed. Luxembourg: European Commission, Publications Office of the European Union; 2010.Google Scholar
- 6.•• Ferlitsch M, Reinhart K, Pramhas S et al. Sex-specific prevalence of adenomas, advanced adenomas, and colorectal cancer in individuals undergoing screening colonoscopy. JAMA. 2011;306(12):1352–8. This recently published study shows a difference of about 10 years in prevalence of advanced adenomas between men and women. PubMedCrossRefGoogle Scholar
- 7.• Nguyen SP, Bent S, Chen Y-H, Terdiman JP. Gender as a risk factor for advanced neoplasia and colorectal cancer: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2009;7:676–81. This meta-analysis confirms that risk for advanced neoplasia is higher in men. PubMedCrossRefGoogle Scholar
- 8.Hoffmeister M, Schmitz S, Karmrodt E, et al. Male sex and smoking have a larger impact on the prevalence of colorectal neoplasm than family history of colorectal cancer. Clin Gastroenterol Hepatol. 2010;8(10):870–6.Google Scholar
- 10.•• Lansdorp-Vogelaar I, van Ballegooijen M, Zauber AG, et al. Individualizing colonoscopy screening by sex and race. Gastrointest Endosc. 2009;70:96–108. In this study, a micro-simulation model was used to estimate cost-effectiveness of individualizing colonoscopy screening by gender and race. PubMedCrossRefGoogle Scholar