Current Colorectal Cancer Reports

, Volume 5, Issue 3, pp 135–139

Evolving end points for clinical trials in advanced colorectal cancer


DOI: 10.1007/s11888-009-0020-y

Cite this article as:
Gill, S. & Sargent, D.J. Curr colorectal cancer rep (2009) 5: 135. doi:10.1007/s11888-009-0020-y


The treatment of advanced colorectal cancer has evolved significantly over recent years. The increasing and justified demand for timely and robust evaluation of emerging therapies has led to the careful evaluation of alternative end points for clinical trials beyond overall survival. This review offers insights into the advantages, limitations, and promise of existing and emerging efficacy end points of interest

Copyright information

© Current Medicine Group, LLC 2009

Authors and Affiliations

  1. 1.Mayo ClinicRochesterUSA

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