Current Cardiology Reports

, 15:426 | Cite as

Acute Hypertensive Response Management in Patients with Acute Stroke

  • Syeda L. AlqadriEmail author
  • Varun Sreenivasan
  • Adnan I. Qureshi
Stroke (C Sila, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Stroke


Acute elevation in blood pressure (acute hypertensive response) is commonly observed in the early period of both ischemic and hemorrhagic stroke. The management of acute hypertensive response depends upon the underlying intracranial pathology. Management of acute hypertensive response has been the focus of many trials and studies such as the SCAST trial, CHHIPS trial, COSSACS trial, INTERACT, and ATACH trial, which are discussed here. However, there were many limitations to these trials including time of presentation, different pathophysiology of ischemic strokes versus hemorrhagic strokes, and patient related factors. Ongoing clinical trials which take these limitations into account include ENCHANTED trial, ATACH II trial, INTERACT 2 trial, and ENOS trial. The results of these trials are expected to modify current guidelines of acute stroke, both ischemic and hemorrhagic, and potentially improve clinical outcomes and quality of life.


Acute ischemic stroke Blood pressure Intracerebral hemorrhage Hypertensive response Penumbra Hematoma Management 


Compliance with Ethics Guidelines

Conflict of Interest

Syeda L. Alqadri, Varun Sreenivasan, and Adnan I. Qureshi declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Syeda L. Alqadri
    • 1
    Email author
  • Varun Sreenivasan
    • 2
  • Adnan I. Qureshi
    • 3
  1. 1.Department of NeurologyUniversity of Mississippi Medical CenterJacksonUSA
  2. 2.Department of MedicineKilpauk Medical CollegeKilpauk, ChennaiIndia
  3. 3.Department of NeurologyUniversity of MinnesotaMinneapolisUSA

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