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Management of Acute Ischemic Stroke

  • Alex Abou-Chebl
Peripheral Vascular Disease (M Shishehbor, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Peripheral Vascular Disease

Abstract

Acute stroke affects about 800,000 patients annually in the US and is the leading cause of disability. It is a complex condition with multiple causes and requires comprehensive but rapid evaluation by stroke specialists working in institutions with well-organized stroke systems of care. Acute stroke treatment is focused on early revascularization with intravenous tPA for those with strokes under 3 hours duration or intra-arterial therapy for most others and those who cannot receive tPA. The latter is evolving rapidly with the advent of stent-retriever embolectomy devices that are poised to revolutionize stroke treatment. Recanalization is associated with neurological recovery in 33–50 % of patients. This also means that many patients may have devastating and life-threatening brain injury, which highlights the need for comprehensive care for the prevention and treatment of medical complications, management of cerebral edema and intracerebral hemorrhage.

Keywords

Acute stroke Cerebral ischemia Intracerebral hemorrhage Thrombolysis Intra-arterial therapy Thrombectomy 

Notes

Disclosure

Conflicts of interest: A. Abou-Chebl: has been the Chair DSMB for Codman Inc.; and is on the speakers' bureaus for BMS/Sanofi.

References

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of NeurologyUniversity of Louisville School of MedicineLouisvilleUSA

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