Current Cardiology Reports

, Volume 14, Issue 2, pp 180–189

Ischemic Mitral Regurgitation: Not Only a Bystander

  • Philippe Unger
  • Julien Magne
  • Chantal Dedobbeleer
  • Patrizio Lancellotti
Valvular Heart Disease (V Nkomo, Section Editor)


Ischemic mitral regurgitation (MR) is a common complication of left ventricular (LV) dysfunction related to chronic coronary artery disease. This complex multifactorial disease involves global and regional LV remodeling, as well as dysfunction and distortion of the components of the mitral valve including the chordae, the annulus, and the leaflets. Its occurrence is associated with a poor prognosis. The suboptimal results obtained with the most commonly used surgical strategy, involving mitral valve annuloplasty with coronary bypass grafting, emphasize the need to develop alternative surgical techniques targeting the causal mechanisms of the disease. A comprehensive preoperative assessment of mitral valve configuration and LV geometry and function and an accurate quantification of MR severity at rest and during exercise may contribute to improve risk stratification and to tailor the surgical strategy according to the individual characteristics of the patient.


Valve Mitral regurgitation Ischemia Left ventricular dysfunction 


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Philippe Unger
    • 1
  • Julien Magne
    • 2
  • Chantal Dedobbeleer
    • 1
  • Patrizio Lancellotti
    • 2
  1. 1.Cardiology Department, Erasme HospitalUniversité Libre de BruxellesBrusselsBelgium
  2. 2.Cardiology DepartmentUniversity of LiègeLiègeBelgium

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