Current Cardiology Reports

, Volume 13, Issue 1, pp 30–37 | Cite as

Interventional Management of Asymptomatic Extracranial Carotid Stenosis



Carotid artery stenosis is a major risk factor for stroke and transient ischemic attack. Although carotid endarterectomy is the established gold standard for carotid revascularization, carotid artery angioplasty and stenting (CAS)—proven by large randomized clinical trials and rigorous registries and supported by improving stent designs, embolic protection, and increasing neurointerventionalist experience—is developing into a safer and more efficacious method of stroke prevention. Today, protected CAS is approved for symptomatic and asymptomatic patients with severe carotid stenosis with high surgical risk. We reviewed recently published data regarding new developments in the use of protected CAS, particularly in patients with carotid stenosis who are either asymptomatic or at low surgical risk.


Extracranial carotid stenting Asymptomatic carotid stenosis SAPPHIRE CREST Ongoing carotid trials 

Clinical Trial Acronyms


Asymptomatic Carotid Atherosclerosis Study


Asymptomatic Carotid Surgery Trial


Asymptomatic Carotid Stenosis, Stenting Versus Endarterectomy Trial


Carotid Artery Revascularization Using the Boston Scientific FilterWire EX/EZ and the EndoTex NexStent


Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare Events


Carotid Revascularization Using Endarterectomy or Stenting Systems


Carotid Revascularization Endarterectomy Versus Stent


European Carotid Surgery Trial


Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis


Imaging in Carotid Angioplasty and Risk of Stroke


International Carotid Stenting Study


North America Symptomatic Carotid Endarterectomy Trial


Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy


Stent-Supported Percutaneous Angioplasty of the Carotid Artery Versus Endarterectomy


Transatlantic Asymptomatic Carotid Intervention Trial


Papers of particular interest, published recently, have been highlighted as: • Of Importance

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of NeurologyUniversity of Louisville School of MedicineLouisvilleUSA
  2. 2.University of Louisville School of MedicineLouisvilleUSA

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