Current Cardiology Reports

, Volume 13, Issue 1, pp 18–23 | Cite as

Intensive Medical Therapy for Asymptomatic Carotid Artery Stenosis



The majority of carotid revascularization procedures are done in patients without recent symptoms of cerebral ischemia (asymptomatic carotid stenosis). In previous studies from the past two decades, the stroke risk associated with asymptomatic carotid stenosis has been estimated to be 2–2.5% per year. Given the relatively benign nature of asymptomatic carotid stenosis, it has been proposed that confining revascularization to a limited, higher-risk subgroup is a sensible strategy. Evidence is accumulating that improved medical therapy has led to a lower risk of stroke in medically treated patients and that ultrasound methods can identify higher-risk patients. These developments are highlighted in this article.


Carotid stenosis Statins Asymptomatic stenosis Transcranial Doppler 

Clinical Trial Acronyms


Asymptomatic Carotid Surgery Trial


North American Symptomatic Carotid Endarterectomy Trial


Oxford Vascular Study


Stent-protected Angioplasty in Asymptomatic Carotid Artery Stenosis Versus Endarterectomy


Stroke Prevention by Aggressive Reduction in Cholesterol Levels


Veterans Affairs Cooperative Study



Conflicts of Interest

P. Bhattacharya: none; S. Chaturvedi works with Abbott Vascular and is an executive committee member for ACT, CAPTURE 2, and PROTECT.


Papers of particular interest, published recently, have been highlighted as: • Of importance

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Neurology & Stroke ProgramWayne State UniversityDetroitUSA

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