Current Cardiology Reports

, Volume 12, Issue 5, pp 440–445

Contrast-Induced Acute Kidney Injury: The At-Risk Patient and Protective Measures


DOI: 10.1007/s11886-010-0129-2

Cite this article as:
Brown, J.R. & Thompson, C.A. Curr Cardiol Rep (2010) 12: 440. doi:10.1007/s11886-010-0129-2


Contrast-induced acute kidney injury (CI-AKI) is a major complication following radiocontrast procedures. In this review, we characterize the recent literature on CI-AKI, risk factors, prevention, biomarkers, and new technologies. The premise of CI-AKI prophylaxis should focus on implementing mandatory standing orders before and after cardiac catheterization for hydration with normal saline or sodium bicarbonate and use of high-dose (1200-mg) N-acetylcysteine. Contrast agents may play a role in preventing CI-AKI. Implement catheter-laboratory technology and awareness to limit the amount of contrast dye used for any patient.


Radiocontrast Nephropathy Kidney injury Cardiac catheterization Prevention Risk factors 

Copyright information

© US Government 2010

Authors and Affiliations

  1. 1.Invasive Cardiology and Vascular MedicineYale University School of MedicineNew HavenUSA
  2. 2.The Dartmouth Institute for Health Policy and Clinical Practice, Section of CardiologyDartmouth Medical SchoolHanoverUSA

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