Current Cardiology Reports

, Volume 11, Issue 2, pp 85–93 | Cite as

Natriuretic peptides in the management of aortic stenosis

Article
First Online:

Abstract

B-type natriuretic peptide (BNP) and its prohormone NT-proBNP are released in response to myocardial wall stress and are established predictors of outcome in heart failure. This article discusses the prognostic value of BNP in aortic stenosis (AS). In recent studies, BNP and NT-proBNP were consistently related to AS severity and symptom status. High or serially rising BNP predicted the short-term need for valve replacement in asymptomatic severe AS. Preoperative BNP or NT-proBNP reflected postoperative outcome. In low-flow low-gradient AS, high BNP greater than 550 pg/mL predicted poor outcome independently of contractile reserve. BNP and NT-proBNP are easy to assess from plasma and improve risk stratification in the whole spectrum of AS.

Keywords

Natriuretic Peptide Aortic Stenosis Mitral Regurgitation Brain Natriuretic Peptide Aortic Valve Replacement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Current Medicine Group, LLC 2009

Authors and Affiliations

  1. 1.Department of CardiologyMedical University of ViennaViennaAustria

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