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Current Cardiology Reports

, Volume 7, Issue 6, pp 435–440 | Cite as

Obstructive sleep apnea and hypertension

  • Krzysztof Narkiewicz
  • Jacek Wolf
  • Francisco Lopez-Jimenez
  • Virend K. Somers
Article

Abstract

There is growing evidence of a causal relationship between obstructive sleep apnea (OSA) and hypertension. Untreated OSA may have direct and deleterious effects on cardiovascular function and structure through several mechanisms, including sympathetic activation, oxidative stress, inflammation, and endothelial dysfunction. OSA may contribute to or augment elevated blood pressure levels in a large proportion of the hypertensive patient population. It is important to consider OSA in the differential diagnosis of hypertensive patients who are obese. OSA should be especially considered in those hypertensive patients who respond poorly to combination therapy with antihypertensive medications.

Keywords

Obstructive Sleep Apnea Sleep Apnea Continuous Positive Airway Pressure Obstructive Sleep Apnea Syndrome Respir Crit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Current Science Inc 2005

Authors and Affiliations

  • Krzysztof Narkiewicz
    • 1
  • Jacek Wolf
  • Francisco Lopez-Jimenez
  • Virend K. Somers
  1. 1.Hypertension Unit, Department of Hypertension and DiabetologyMedical University of GdanskGdanskPoland

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