Hypertriglyceridemia and risk of coronary heart disease
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Mounting evidence indicates that elevated triglyceride level is a risk factor for coronary heart disease (CHD). The role of triglyceride as a causative agent for CHD is less clear. Hyper-triglyceridemia is frequently associated with a set of complex metabolic abnormalities, including low high-density lipoprotein cholesterol, small dense low-density lipoprotein, central obesity, insulin resistance, and type 2 diabetes. Understanding the physiologic processes that lead to the metabolic disturbances associated with hypertriglyceridemia is essential in investigating the effect of triglyceride on CHD risk.
KeywordsTriglyceride Familial Combine Hyperlipidemia Lipoprotein Lipase Gene Lipoprotein Lipase Deficiency Paris Prospective Study
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