Current Atherosclerosis Reports

, 16:390

Cardiometabolic Impact of Non-Statin Lipid Lowering Therapies

  • Parag Goyal
  • Leon I. Igel
  • Keith LaScalea
  • William B. Borden
Nonstatin Drugs (WB Borden, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Nonstatin Drugs


Among the range of lipid modifying medications currently available, statins clearly stand as the primary agent capable of reducing cardiovascular risk. While non-statin lipid-lowering drugs improve lipid parameters, their impact on clinical outcomes is less clear, thus necessitating an even closer look at ancillary effects. Recent studies have reported the potential cardiometabolic effects of statins, yet considerably less information has been published about cardiometabolic changes associated with non-statin lipid-lowering agents. This review describes the cardiometabolic profile of non-statin lipid-lowering agents—fibrates, niacin, omega-3 polyunsaturated fatty acids, ezetimibe, and bile acid sequestrants—and therefore aims to facilitate informed decision-making in the pharmacologic management of lipid abnormalities.


Lipids Fibrates Cardiovascular disease Diabetes mellitus type 2 Niacin Omega-3 polyunsaturated fatty acids PUFAs Ezetimibe Bile acid sequestrants 


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Parag Goyal
    • 1
  • Leon I. Igel
    • 1
  • Keith LaScalea
    • 1
  • William B. Borden
    • 1
  1. 1.New YorkUSA

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