Role of Metabolic Surgery in Less Obese or Non-Obese Subjects with Type 2 Diabetes: Influence Over Cardiovascular Events

  • Ricardo Cohen
  • Pedro Paulo Caravatto
  • Tarissa Petry
  • David Cummings
Lipid and Metabolic Effects of Gastrointestinal Surgery (FR Rubino, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Lipid and Metabolic Effects of Gastrointestinal Surgery


Bariatric surgery was initially developed as a tool for weight reduction only, but it is gaining increasing popularity because of its remarkable effect on glucose metabolism in morbidly obese and less obese patients. Recent publications have shown the good results of metabolic surgery, creating a new field of clinical research that is currently overflowing in the medical community with outstanding high-quality data. In morbidly obese population, there is compelling data on long term cardiovascular risk reduction and mortality, coming from longitudinal prospective studies and systematic reviews. Numbers range from 33 to 92 % of decrease in fatal and nonfatal cardiovascular events . In low body mass index (BMI) diabetics, there is an increasing number of reported good outcomes after metabolic surgery with the aim to treat type 2 diabetes (T2DM). There is scarce information on cardiovascular outcomes in non–morbidly obese subjects, but the extraordinary glucose, lipid and blood pressure control in the published series are suggesting good long-term effects on cardiovascular risk profile and mortality. The papers review was comprehensive, including the available randomized controlled trials, long-term prospective series and systematic reviews.


Type 2 diabetes mellitus Metabolic surgery Bariatric surgery Obesity Gastrointestinal surgery 


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Ricardo Cohen
    • 1
  • Pedro Paulo Caravatto
    • 1
  • Tarissa Petry
    • 1
  • David Cummings
    • 2
  1. 1.The Center of Excellence of Metabolic and Bariatric SurgeryOswaldo Cruz HospitalSão PauloBrazil
  2. 2.Diabetes and Obesity Center of Excellence and Veterans Affairs Puget Sound Health Care SystemUniversity of Washington School of MedicineSeattleUSA

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