Treatment of Symptomatic Carotid Stenosis: Carotid Stent Placement Versus Endarterectomy

Cardiovascular Disease and Stroke (D Leifer and JE Safdieh, Section Editors)
First Online:
Part of the following topical collections:
  1. Topical Collection on Cardiovascular Disease and Stroke

Abstract

The mainstay of treatment options for symptomatic carotid stenosis is focused around medical management, carotid endarterectomy, and carotid angioplasty and stent placement. The International Carotid Stenting Study (ICSS), also called Carotid and Vertebral Artery Transluminal Angioplasty Study 2 (CAVATAS 2), the Stent-Supported Percutaneous Angioplasty of the Carotid Artery Versus Endarterectomy (SPACE) trial, the Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial, the Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy (SAPPHIRE) trial, and the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) were five major trials which compared carotid endarterectomy and carotid angioplasty and stent placement. We review the results of the trials and incorporation of the results into clinical decision making.

Keywords

Carotid endarterectomy Carotid artery stenosis Carotid angioplasty Carotid stent placement Ischemic stroke Atherosclerosis 
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Notes

Conflict of Interest

Syeda L. Alqadri declares no conflict of interest.

Adnan I Qureshi declares no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of NeurologyUniversity of Mississippi Medical CenterJacksonUSA
  2. 2.Zeenat Qureshi Stroke Research CenterUniversity of MinnesotaMinneapolisUSA
  3. 3.Department of NeurologyUniversity of MinnesotaMinneapolisUSA

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