Current Atherosclerosis Reports

, Volume 13, Issue 2, pp 138–146

Obstructive Sleep Apnea and the Risk for Cardiovascular Disease


DOI: 10.1007/s11883-011-0161-8

Cite this article as:
Kohli, P., Balachandran, J.S. & Malhotra, A. Curr Atheroscler Rep (2011) 13: 138. doi:10.1007/s11883-011-0161-8


Obstructive sleep apnea (OSA) is a common disorder with major neurocognitive and cardiovascular sequelae. It is estimated that more than one quarter of the population is at risk for OSA, with increased prevalence noted in populations with hypertension, coronary artery disease, stroke, and atrial fibrillation. A number of epidemiologic and mechanistic studies have recently generated interest in the role of OSA in the pathophysiology of cardiovascular disease, a link that continues to require extensive investigation. This chapter reviews these epidemiologic studies, the current understanding of the mechanisms by which OSA may contribute to the progression of cardiovascular diseases, and the effects of OSA treatment on cardiovascular disease outcomes.


Lung Heart Sleep apnea Cardiovascular Hypoxemia Vascular 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Puja Kohli
    • 1
  • Jay S. Balachandran
    • 1
  • Atul Malhotra
    • 1
  1. 1.Brigham and Women’s HospitalBrooklineUSA

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