Modulation of inflammation by Nutritional Interventions

  • Francesco VisioliEmail author
  • Andrea Poli
  • Doriane Richard
  • Rodolfo Paoletti
Invited Commentary


Polyphenol Resveratrol Mediterranean Diet Moderate Alcohol Consumption Sparkling Wine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Ross R: Atherosclerosis—an inflammatory disease. N Engl J Med 1999, 340:115–126.PubMedCrossRefGoogle Scholar
  2. 2.
    Lichtenstein AH, Appel LJ, Brands M, et al.: Summary of American Heart Association Diet and Lifestyle Recommendations revision 2006. Arterioscler Thromb Vasc Biol 2006, 26:2186–2191.PubMedCrossRefGoogle Scholar
  3. 3.
    ISSFAL. Available at Accessed on May 15, 2008.
  4. 4.
    Harris WS: Omega-3 fatty acids and cardiovascular disease: a case for omega-3 index as a new risk factor. Pharmacol Res 2007, 55:217–223.PubMedCrossRefGoogle Scholar
  5. 5.
    Harris WS: International recommendations for consumption of long-chain omega-3 fatty acids. J Cardiovasc Med 2007, 8(Suppl 1):S50–S52.Google Scholar
  6. 6.
    Ferrucci L, Cherubini A, Bandinelli S, et al.: Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J Clin Endocrinol Metab 2006, 91:439–446.PubMedCrossRefGoogle Scholar
  7. 7.
    Ariel A, Serhan CN: Resolvins and protectins in the termination program of acute inflammation. Trends Immunol 2007, 28:176–183.PubMedCrossRefGoogle Scholar
  8. 8.
    Richard D, Kefi K, Barbe U, et al.: Polyunsaturated fatty acids as antioxidants. Pharmacol Res 2008, 57:451–455.PubMedCrossRefGoogle Scholar
  9. 9.
    Sacks FM, Campos H: Polyunsaturated fatty acids, inflammation, and cardiovascular disease: time to widen our view of the mechanisms. J Clin Endocrinol Metab 2006, 91:398–400.PubMedCrossRefGoogle Scholar
  10. 10.
    De Caterina R, Liao JK, Libby P: Fatty acid modulation of endothelial activation. Am J Clin Nutr 2000, 71:213S–223S.PubMedGoogle Scholar
  11. 11.
    Trichopoulou A, Critselis E: Mediterranean diet and longevity. Eur J Cancer Prev 2004, 13:453–456.PubMedCrossRefGoogle Scholar
  12. 12.
    Chrysohoou C, Panagiotakos DB, Pitsavos C, et al.: Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: The ATTICA Study. J Am Coll Cardiol 2004, 44:152–158.PubMedCrossRefGoogle Scholar
  13. 13.
    Fuentes F, Lopez-Miranda J, Sanchez E, et al.: Mediterranean and low-fat diets improve endothelial function in hypercholesterolemic men. Ann Intern Med 2001, 134:1115–1119.PubMedGoogle Scholar
  14. 14.
    Visioli F, Bogani P, Grande S, et al.: Local food and cardioprotection: the role of phytochemicals. Forum Nutr 2006, 59:116–129.PubMedCrossRefGoogle Scholar
  15. 15.
    Biesalski HK: Polyphenols and inflammation: basic interactions. Curr Opin Clin Nutr Metab Care 2007, 10:724–728.PubMedCrossRefGoogle Scholar
  16. 16.
    Basu A, Lucas EA: Mechanisms and effects of green tea on cardiovascular health. Nutr Rev 2007, 65:361–375.PubMedCrossRefGoogle Scholar
  17. 17.
    Stevenson DE, Hurst RD: Polyphenolic phytochemicals—just antioxidants or much more? Cell Mol Life Sci 2007, 64:2900–2916.PubMedCrossRefGoogle Scholar
  18. 18.
    Bogani P, Galli C, Villa M, Visioli F: Postprandial antiinflammatory and antioxidant effects of extra virgin olive oil. Atherosclerosis 2007, 190:181–186.PubMedCrossRefGoogle Scholar
  19. 19.
    Klatsky AL: Alcohol, cardiovascular diseases and diabetes mellitus. Pharmacol Res 2007, 55:237–247.PubMedCrossRefGoogle Scholar
  20. 20.
    Albert MA, Glynn RJ, Ridker PM: Alcohol consumption and plasma concentration of C-reactive protein. Circulation 2003, 107:443–447.PubMedCrossRefGoogle Scholar
  21. 21.
    Imhof A, Froehlich M, Brenner H, et al.: Effect of alcohol consumption on systemic markers of inflammation. Lancet 2001, 357:763–767.PubMedCrossRefGoogle Scholar
  22. 22.
    Kleinhenz DJ, Sutliff RL, Polikandriotis JA, et al.: Chronic ethanol ingestion increases aortic endothelial nitric oxide synthase expression and nitric oxide production in the rat. Alcohol Clin Exp Res 2008, 32:148–154.PubMedCrossRefGoogle Scholar
  23. 23.
    Vazquez-Agell M, Sacanella E, Tobias E, et al.: inflammatory markers of atherosclerosis are decreased after moderate consumption of cava (sparkling wine) in men with low cardiovascular risk. J Nutr 2007, 137:2279–2284.PubMedGoogle Scholar
  24. 24.
    Vinson JA, Mandarano M, Hirst M, et al.: Phenol antioxidant quantity and quality in foods: beers and the effect of two types of beer on an animal model of atherosclerosis. J Agric Food Chem 2003, 51:5528–5533.PubMedCrossRefGoogle Scholar
  25. 25.
    Soleas GJ, Diamandis EP, Goldberg DM: The world of resveratrol. Adv Exp Med Biol 2001, 492:159–182.PubMedGoogle Scholar

Copyright information

© Current Medicine Group LLC 2008

Authors and Affiliations

  • Francesco Visioli
    • 1
    Email author
  • Andrea Poli
  • Doriane Richard
  • Rodolfo Paoletti
  1. 1.UMR 7079Université Pierre et Marie CurieParisFrance

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