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New Insights into Ragweed Pollen Allergens

  • Véronique Bordas-Le Floch
  • Rachel Groeme
  • Henri Chabre
  • Véronique Baron-Bodo
  • Emmanuel Nony
  • Laurent Mascarell
  • Philippe Moingeon
Allergens (RK Bush and JA Woodfolk, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Allergens

Abstract

Pollen allergens from short ragweed (Ambrosia artemisiifolia) cause severe respiratory allergies in North America and Europe. To date, ten short ragweed pollen allergens belonging to eight protein families, including the recently discovered novel major allergen Amb a 11, have been recorded in the International Union of Immunological Societies (IUIS) allergen database. With evidence that other components may further contribute to short ragweed pollen allergenicity, a better understanding of the allergen repertoire is a requisite for the design of proper diagnostic tools and efficient immunotherapies. This review provides an update on both known as well as novel candidate allergens from short ragweed pollen, identified through a comprehensive characterization of the ragweed pollen transcriptome and proteome.

Keywords

Allergens Ambrosia artemisiifolia Mass spectrometry RNA sequencing Short ragweed 

Notes

Compliance with Ethics Guidelines

Conflict of Interest

Drs. Bordas-Le Floch, Rachel Groeme has a MSc, Chabre, Baron-Bodo, Nony, Mascarell, and Moingeon declare that they are employed by Stallergenes SA.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Véronique Bordas-Le Floch
    • 1
  • Rachel Groeme
    • 1
  • Henri Chabre
    • 1
  • Véronique Baron-Bodo
    • 1
  • Emmanuel Nony
    • 1
  • Laurent Mascarell
    • 1
  • Philippe Moingeon
    • 1
  1. 1.StallergenesAntony cedexFrance

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