IgG4-Related Ophthalmic Disease: Pooling of Published Cases and Literature Review

  • Albert Wu
  • Nicholas H Andrew
  • Alan A McNab
  • Dinesh Selva
Autoimmunity (TK Tarrant, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Autoimmunity

Abstract

In recent years, IgG4-related ophthalmic disease (IgG4-ROD) has emerged as a common cause of orbital inflammation, accounting for a substantial proportion of idiopathic orbital inflammation and lymphoid hyperplasia. The last pooled analysis of published cases was conducted in 2012, but a large number of new cases have been added to the literature since then. In this review, we present the demographic, clinical, histological, and treatment data for 172 published cases of biopsy-confirmed IgG4-ROD. Results are accompanied by a review of the relevant literature.

Keywords

Immunoglobulin G4 Orbital Orbit Ocular Dacryoadenitis Lacrimal 

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Albert Wu
    • 1
  • Nicholas H Andrew
    • 1
  • Alan A McNab
    • 2
  • Dinesh Selva
    • 1
  1. 1.South Australian Institute of OphthalmologyUniversity of AdelaideAdelaideAustralia
  2. 2.Centre for Eye Research AustraliaUniversity of MelbourneMelbourneAustralia

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