Allergic Contact Dermatitis in Children: Review of the Past Decade

  • Shehla Admani
  • Sharon E. JacobEmail author
Part of the following topical collections:
  1. Topical Collection on Allergic Skin Diseases


Allergic contact dermatitis (ACD) is a type IV delayed hypersensitivity reaction. During the last decade, there has been a heightened awareness of this disease in the pediatric population. The gold standard for diagnosis is patch testing. The prevalence of positive patch tests in referred children with suspected ACD ranges from 27 to 95.6 %. The most common allergens in children in North America are nickel, neomycin, cobalt, fragrance, Myroxylon pereirae, gold, formaldehyde, lanolin/wool alcohols, thimerosal, and potassium dichromate. The relationship between ACD and atopic dermatitis (AD) is complicated with conflicting reports of prevalence in the literature; however, in a patient with dermatitis not responding to traditional therapies, or with new areas of involvement, ACD should be considered as part of the work-up.


Allergic contact dermatitis Patch test Pediatric Children Allergen Allergic sensitization Atopic dermatitis 


Compliance with Ethics Guidelines

Conflict of Interest

Sharon E. Jacob is a board member for the American Contact Dermatitis Society and has served as a consultant for Johnson & Johnson.

Shehla Admani declares that she has no conflict of interest.

Dr. Jacob and Dr. Admani are independent investigators for the PREA-2 study evaluating the safety and efficacy of the 3 panel T.R.U.E. ™ test in children.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Division of Dermatology, Rady Children’s HospitalUniversity of California San DiegoSan DiegoUSA
  2. 2.San Diego and Rady Children’s HospitalUniversity of CaliforniaSan DiegoUSA

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