Current Allergy and Asthma Reports

, Volume 12, Issue 4, pp 339–345 | Cite as

Sesame Seed Food Allergy

  • Ilan Dalal
  • Michael Goldberg
  • Yitzhak KatzEmail author


The number of reports regarding sesame seed food allergy (SFA) has increased significantly worldwide over the past two decades, either due to a genuine increase in SFA or merely an increase in its awareness. Its prevalence is difficult to estimate due to the lack of well designed prospective population-based studies. Based on the available data, we estimate that SFA affects 0.1–0.2 % of the population, in areas where the food is available. Albeit this prevalence appears to be relatively low, it is approximately one-half of that of persistent cow’s milk allergy. While only one fatality has been reported, the significant number of SFA patients presenting as anaphylaxis indicates the potential risk. Many reports based the diagnosis of SFA on sensitization criteria alone, particularly amongst atopic dermatitis patients. Elimination of sesame from the diet of these children utilizing such criteria is not justified, and may even increase the risk for developing SFA.


Food allergy Sesame seed SPT Specific IgE Oral Challenge Anaphylaxis 



Atopic dermatitis


Double blind placebo controlled food challenge


Immunoglobulin E


Oral challenge


Sesame-seed food allergy


Specific immunoglobulin E


Skin prick test



Dr. Goldberg is funded by a Kamea grant from the Chief Scientist Office, Ministry of Health, Israel.


No potential conflicts of interest relevant to this article were reported.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Pediatric Allergy/Immunology Unit, E. Wolfson Medical Center, Sackler School of MedicineTel-Aviv UniversityHolonIsrael
  2. 2.The Institute of Allergy, Pulmonary and ImmunologyAssaf Harofeh Medical CenterZerifinIsrael

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