Current Allergy and Asthma Reports

, Volume 12, Issue 3, pp 240–245 | Cite as

Migraine and Allergy: A Review and Clinical Update

  • Mark E. Mehle


Migraine and allergy are both common diseases. Many patients suffer from both, and the vast majority of patients with “sinus headache” complaints are found to have migraine, making migraine identification important to allergists. This review addresses the possibility that allergy and migraine are comorbid conditions, focusing on epidemiology, shared biochemical pathways, and underlying mechanisms. Therapeutic implications of this possible relationship have been the subject of several recent studies, making a review of this association timely and prudent.


Allergy Migraine Sinus headache Epidemiology Mechanisms Food allergy Trigger IgG Muscle contraction headache 



Dr. Mehle has served on Speaker's Bureau for GSK and Alcon and has served on rhinitis advisory boards for Merck and Teva.


Papers of particular interest, published recently, have been highlighted as: •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Northeast Ohio Medical UniversityNorth OlmstedUSA

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