Current Allergy and Asthma Reports

, Volume 12, Issue 1, pp 55–63

Vaccines and Immunomodulatory Therapies for Food Allergy

Anaphylaxis and Drug Allergy (P Lieberman and S Spector, Section Editors)

Abstract

The apparent increase in food allergy prevalence has led to a surge in the amount of clinical and basic science research dedicated to the field. At the current time, allergen avoidance remains the cornerstone of treatment; however, recent clinical trials investigating various forms of immunotherapy have opened doors to the possible future application of an active treatment strategy in everyday practice. In addition, improvements in molecular biology have allowed researchers to purify, clone, and modify allergens, thus laying the groundwork for research on vaccines using modified proteins of decreased allergenicity. Finally, various allergen-nonspecific immunomodulatory therapies are also being investigated as a means to alter the immune response to food allergens. With these emerging therapeutic strategies, it is hoped that practitioners will have options in caring for their food-allergic patients in the near future.

Keywords

Food allergy Immunotherapy Immunomodulatory Treatment Therapy Vaccine Peptide Epitope Chinese herbal therapy Omalizumab Sublingual Peanut 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of PediatricsMount Sinai School of MedicineNew YorkUSA

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