Current Allergy and Asthma Reports

, Volume 12, Issue 1, pp 55–63 | Cite as

Vaccines and Immunomodulatory Therapies for Food Allergy

  • Jay A. LiebermanEmail author
  • Anna Nowak-Węgrzyn
Anaphylaxis and Drug Allergy (P Lieberman and S Spector, Section Editors)


The apparent increase in food allergy prevalence has led to a surge in the amount of clinical and basic science research dedicated to the field. At the current time, allergen avoidance remains the cornerstone of treatment; however, recent clinical trials investigating various forms of immunotherapy have opened doors to the possible future application of an active treatment strategy in everyday practice. In addition, improvements in molecular biology have allowed researchers to purify, clone, and modify allergens, thus laying the groundwork for research on vaccines using modified proteins of decreased allergenicity. Finally, various allergen-nonspecific immunomodulatory therapies are also being investigated as a means to alter the immune response to food allergens. With these emerging therapeutic strategies, it is hoped that practitioners will have options in caring for their food-allergic patients in the near future.


Food allergy Immunotherapy Immunomodulatory Treatment Therapy Vaccine Peptide Epitope Chinese herbal therapy Omalizumab Sublingual Peanut 



No potential conflicts of interest relevant to this article were reported.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of PediatricsMount Sinai School of MedicineNew YorkUSA

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