Current Allergy and Asthma Reports

, Volume 10, Issue 6, pp 460–467

Molecular- and Flow Cytometry-based Diagnosis of Primary Immunodeficiency Disorders

Article
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Abstract

Primary immunodeficiencies are an expanding group of genetic disorders resulting in recurrent and/or severe infections, autoimmunity, or autoinflammation. The laboratory plays a critical role in the diagnosis of these conditions given their frequently overlapping signs and symptoms. We discuss here advances in flow cytometry and molecular techniques applied to the study of primary immunodeficiencies.

Keywords

Flow cytometry Genetics Primary immunodeficiency Diagnosis Molecular 

Copyright information

© US Government 2010

Authors and Affiliations

  1. 1.Department of Laboratory Medicine, Clinical CenterNational Institutes of HealthBethesdaUSA

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