Although most food-allergic reactions occur after ingestion of nonpackaged food products, the food industry has been subjected to increasing scrutiny of their allergen controls; the resulting impact on the industry has been remarkable. Undeclared food allergens have been responsible for many food product recalls during the past 13 years, and the food industry has made significant investment, effort, and improvements in allergen control during this time. Recently, tests for some allergenic foods have been commercialized, and proven useful to the industry in controlling allergens and helpful for regulatory agencies investigating food-allergic consumer complaints. However, testing methods still do not exist for some of the common allergenic foods. Labeling initiatives have been pursued to make ingredient listings more easily understood by food-allergic consumers, but further improvements could still be made. Additional research to determine eliciting doses for allergenic foods is needed to enable science-based risk assessment and risk management.
KeywordsFood Allergy Allergy Clin Immunol Allergenic Food Good Manufacturing Practice Shared Equipment
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References and Recommended Reading
- 1.Bock SA, Munoz-Furlong A, Sampson HA: Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol 2001, 107:191–193. This paper describes a series of 32 fatal food anaphylaxis reactions and shows which foods were responsible. There are several interesting findings in this paper, such as most individuals had asthma, the lack of availability of epinephrine appeared to be a factor, and peanuts and tree nuts were responsible for more than 90% of the fatal reactions. This is the most comprehensive study of fatal food-induced anaphylactic reactions to date.PubMedCrossRefGoogle Scholar
- 2.Food and Agriculture Organization of the United Nations: Report of the FAO Technical Consultation on Food Allergies. Rome, Italy. November 13–14. 1995.Google Scholar
- 3.Deibel K, Trautman T, deBoom T, et al.: A comprehensive approach to reducing the risk of allergens in foods. J Food Prot 1997, 60:426–441.Google Scholar
- 5.Vierk K, Falci K, Wolyniak C, Klontz KC: Recalls of foods containing undeclared allergens reported to the US Food and Drug Administration, fiscal year 1999. J Allergy Clin Immunol 2002, 109:1022–1026. In this paper, the US Food and Drug Administration food product recalls due to undeclared food allergens are summarized. Factors contributing to the recalls are discussed, and the circumstances under which many of the problems were discovered are indicated.PubMedCrossRefGoogle Scholar
- 10.Wensing M, Koppelman SJ, Penninks AH, et al.: Hidden hazelnut is a threat to allergic patients. Allergy 2001, 56:191–192. This article describes the investigation of allergic reactions in a hazelnutallergic patient that was eventually traced to a chocolate spread that was not supposed to contain hazelnut. Immunochemical analysis assisted in the identification of the unexpected source of reactions.PubMedCrossRefGoogle Scholar
- 13.Vadas P, Perelman B: Presence of undeclared peanut protein in chocolate bars purchased in the Toronto area. Can J Allergy Clin Immunol 2001, 6:116–117. This paper focuses on an investigation of six different chocolate products obtained from the retail marketplace in Canada and tested using a commercial peanut detection ELISA kit. The data show undeclared peanut in some products.Google Scholar
- 16.Taylor SL, Hefle SL, Bindslev-Jensen C, et al.: Factors affecting the determination of threshold doses for allergenic foods: How much is too much? J Allergy Clin Immunol 2002, 109:24–30. The existing information in medical literature on minimum eliciting doses of allergenic foods is examined, and key issues in making riskmanagement decisions on the basis of such information are identified. A good description of most of the issues surrounding eliciting dose studies is provided, and some lowest provoking dose data are summarized from the literature.PubMedCrossRefGoogle Scholar
- 18.Joshi P, Mofidi S, Sicherer SH: Interpretation of commercial food ingredient labels by parents of food-allergic children. J Allergy Clin Immunol 2002, 109:1019–1021. Given the current labeling regulations, many parents of food-allergic children cannot correctly identify some allergenic foods in ingredient listings.PubMedCrossRefGoogle Scholar
- 19.Taylor SL, Hefle SL: Food Allergy Issues Alliance and food allergen labeling guidelines. Food Allergy Intolerance 2002, 3:37–42.Google Scholar
- 20.Taylor SL, Hefle SL: Good manufacturing practices for allergenic foods: packaging and labeling strategies. Food Allergy Intolerance 2001, 2:53–58.Google Scholar