Current Allergy and Asthma Reports

, Volume 3, Issue 1, pp 47–53 | Cite as

Latex-fruit syndrome

  • Carlos Blanco


Natural rubber latex immunoglobulin E-mediated hypersensitivity is probably one of the most relevant challenges that has been faced in the treatment of allergies during recent years. Additionally, allergen cross-reactivity has arisen as another very important problem, in the difficulty in diagnosing it and in its clinical implications. It is clear that some latex allergens cross-react with plant-derived food allergens, the so-called latex-fruit syndrome, with evident clinical consequences. Although the foods most frequently involved are banana, avocado, kiwi, and chestnut, several others are also implicated. Investigations point to a group of defense-related plant proteins, class I chitinases, which cross-react with a major latex allergen, hevein, as the panallergens responsible for the syndrome. This review focuses on our current understanding of the latex-fruit syndrome.


Food Allergy Allergy Clin Immunol Natural Rubber Latex Food Oral Challenge Latex Allergy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Current Science Inc. 2003

Authors and Affiliations

  • Carlos Blanco
    • 1
  1. 1.Servicio de AlergiaHospital Universitario Dr. Negrín, c/Barrenco de la Ballena s/nSpain

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