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Current Treatment Options in Oncology

, Volume 6, Issue 3, pp 209–214 | Cite as

Pediatric myelodysplastic syndromes

  • Charlotte Marie Niemeyer
  • Christian Peter Kratz
  • Henrik Hasle
Article

Opinion statement

A new classification of myelodysplastic and myeloproliferative diseases in childhood has greatly facilitated the diagnosis of these uncommon disorders. Because hematopoietic stem cell transplantation (HSCT) can cure more than half of the affected children, palliative treatment strategies often applied in adult myelodysplastic syndrome (MDS) are of little importance in pediatric MDS. Unraveling some of the underlying genetic factors predisposing to MDS at a young age may give important insights into leukemogenesis in the elderly.

Keywords

Acute Myeloid Leukemia Hematopoietic Stem Cell Transplantation Aplastic Anemia Myelodysplastic Syndrome Amifostine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Current Science Inc 2005

Authors and Affiliations

  • Charlotte Marie Niemeyer
    • 1
  • Christian Peter Kratz
  • Henrik Hasle
  1. 1.Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent MedicineUniversity of FreiburgFreiburgGermany

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