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Placental weights from normal deliveries in Ireland

  • Orlagh O’Brien
  • Mary F. HigginsEmail author
  • Eoghan E. Mooney
Original Article
  • 2 Downloads

Abstract

Background

The weight of the delivered placenta gives a useful representation of placental function in utero. In the absence of Irish data, many pathologists rely on data from other populations, many of which are now 15 to 30 years old. The development of a population-specific nomogram would aid in the examination of placentas after delivery, allowing pathologists and medical scientists to more easily distinguish between placental physiological changes and pathology.

Aims

To record placental weights among women having a singleton delivery in Dublin and to establish median placental weights for each gestational age after 37 weeks.

Methods

Prospective cohort study in a Tertiary level University Hospital. All singleton pregnancies were included; stillbirths, multiple gestations, and cases with obstetric complications involving the placenta were excluded. The placentas were weighed both untrimmed and trimmed with standard scales. Demographic features including birth weight and maternal parity were also recorded.

Results

Four hundred thirty placentas were weighed over a 6-week period. A median term placental weight based on gestational age was established, with a range from the tenth to ninetieth centiles.

Conclusion

The weight of the placenta is one of several measurements that are easy to acquire, and when recorded in a systematic fashion, provide information not just on an individual, but also on a population basis. Birth weights have increased over the last century, and this study provides national data helping distinction between placental physiology and pathology.

Keywords

Birth Ireland Normogram Placental weights 

Notes

Acknowledgements

The authors would like to acknowledge Mr. John Long, Senior Anatomic Pathology Technician.

Contribution to authorship

All three authors met the criteria for authorship—EEM and MH conceived and planned the study, OO’B obtained samples and performed the measurements, and all three authors analysed data and wrote the paper.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethics

This study was deemed exempt from Ethics Committee approval as data was completely anonymised.

References

  1. 1.
    Wallace JM, Bhattacharya S, Horgan GW (2013) Gestational age, gender and parity specific centile charts for placental weight for singleton deliveries in Aberdeen UK. Placenta. 34(3):269–274CrossRefGoogle Scholar
  2. 2.
    Almog B, Shehata F, Aljabri S, Levin I, Shalon-Paz E, Shirm A (2011) placenta weight percentile curves for singleton and twin deliveries. Placenta. 32(1):58–62CrossRefGoogle Scholar
  3. 3.
    Teng J, Chang T, Reyes C, Nelson KB (2012) Placental weight and neurologic outcome in the infant: a review. J Matern Fetal Neonatal Med 25:2082–2087CrossRefGoogle Scholar
  4. 4.
    Pinar H, Sung CJ, Oyer CE, Singer DB (1996) Reference values for singleton and twin placental weights. Pediatr Pathol Lab Med 16:901–907CrossRefGoogle Scholar
  5. 5.
    Yee KT, Mooney EE, Ariel I et al (2016) Sampling and definition of placental lesions. Amsterdam Placental Workshop Group Consensus Statement. Arch Pathol Lab Med 140:698–713Google Scholar
  6. 6.
    Barker DJP, Thornburg KL (2013) Placental programming of chronic diseases, cancer and lifespan: a review. Placenta 34:841–845CrossRefGoogle Scholar
  7. 7.
    Heinonen S, Taipale P, Saarikokski S (2001) Weights of placentae from small for gestational age infants revisited. Placenta 22:399–404CrossRefGoogle Scholar
  8. 8.
    Audette MC, Kingdom J (2018) Screening for fetal growth restriction and placental insufficiency. Semin Fetal Neonatal Med 23(2):119–125CrossRefGoogle Scholar
  9. 9.
    Luque-Fernandez MA, Ananth CV, Jaddoe VW, Gaillard R, Albert PS, Schomaker M, McElduff P, Enquobahrie DA, Gelaye B, Williams MA (2015) Is the fetoplacental ratio a differential marker of fetal growth restriction in small for gestational age infants? Eur J Epidemiol 30(4):331–334CrossRefGoogle Scholar
  10. 10.
    Altman D, Chitty LS (1993) Design and analysis of studies to derive charts of fetal size. Ultrasound Obstet Gynecol 3(6):378–384CrossRefGoogle Scholar

Copyright information

© Royal Academy of Medicine in Ireland 2019

Authors and Affiliations

  • Orlagh O’Brien
    • 1
  • Mary F. Higgins
    • 2
    Email author
  • Eoghan E. Mooney
    • 3
  1. 1.UCD School of MedicineUniversity College DublinDublin 4Republic of Ireland
  2. 2.UCD Perinatal Research Centre, National Maternity HospitalUniversity College DublinDublin 2Republic of Ireland
  3. 3.Department of Pathology & Laboratory MedicineNational Maternity HospitalDublin 2Republic of Ireland

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