Advertisement

Irish Journal of Medical Science (1971 -)

, Volume 188, Issue 1, pp 333–336 | Cite as

Frequency of Behçet’s disease among a group of visually impaired adults

  • Oguz Abdullah UyarogluEmail author
  • Emrah Seyhoglu
  • Abdulsamet Erden
  • Cevanşir Vahabov
  • Hakan Babaoglu
  • Berkan Armagan
  • Alper Sari
  • Levent Kilic
  • Olcay Tatar
  • Sule Apras Bilgen
  • Omer Karadag
  • Umut Kalyoncu
Original Article
  • 45 Downloads

Abstract

Background

Behçet’s disease (BD) is one of the reasons of acquired visual impairment among young adults. Ocular involvement is a significant cause of disability in BD. The objective of this study is to assess the prevalence of BD among a group of adults who has visual impairment.

Methods

Ankara Metropolitan Municipality Education and Technology Center is one of the official institutions which records and follows the demographic data of visually impaired people in Turkey. In November 2014, there were 675 visually impaired people recorded at this center. Medical history was taken from 294 adults by phone in November and December of 2014. Participants were asked if the visual impairment had been either acquired or congenital. If the patients had BD or suspicious BD, they were recalled for detailed investigation which would be carried out by an internist, a rheumatologist and an ophthalmologist.

Results

Two hundred thirteen of 294 (72.4%) visually impaired adults were male. One hundred nine of 294 (37.1%) had acquired visual impairment. Six (5.5%) of those 109 patients had BD. Overall prevalence of BD among study group was 2.04%.The median age of people with BD was 35 years. The median age at BD diagnosis was 16.5 years and the median duration from diagnosis to visual loss was 2.5 years.

Conclusion

BD is still one of the causes of acquired visual impairment in Turkey. In this study, BD prevalence among a visually impaired adult group was 2.04%. BD accounted for 5.5% among adults who had acquired visual impairment. In a study of 1965, BD prevalence among people with acquired blindness was 12%. However, this study was conducted at pre-immunosuppressive period. Our prevalence is obviously lower than those studies. Extended population-based studies are needed for population estimations.

Keywords

Acquired visual impairment Behçet’s disease Blindness Ocular involvement Visual impairment 

Notes

Compliance with ethical standards

At the beginning of the phone interviews, verbal informed consents were obtained from everyone attending the study. This study has been approved by Hacettepe University Ethics Commission (Approval number: GO 16/287 - 23). Survey was conducted in accordance with the Declaration of Helsinki.

Conflict of interest

The authors declare that there is no conflict of interest.

References

  1. 1.
    Krumpaszky H, Dietz K, Mickler A, Selbmann H (1999) Mortality in blind subjects. Ophthalmologica 213:48–53CrossRefGoogle Scholar
  2. 2.
    Pascolini D, Mariotti SP (2012) Global estimates of visual impairment: 2010. Br J Ophthalmol 96:614–618CrossRefGoogle Scholar
  3. 3.
    State Institute of Statistics, State Planning Organization. Turkey disability survey 2002. Ankara, Turkey, 2009.Publication no: 2913. Available from: http://kutuphane.tuik.gov.tr/pdf/0014899.pdf
  4. 4.
    Ozyazgan Y, Ucar D, Hatemi G, Yazici Y (2015) Ocular involvement of Behçet’s syndrome:a comprehensive review. Clin Rev Allergy Immunol 49:298–306CrossRefGoogle Scholar
  5. 5.
    Mochizuki M, Akduman L, Nussenblatt RB (1996) Behcet’s disease. In: Pepose JS, Holland GN, Wilhelmus KR (eds) Ocular infection and immunity. Mosby, St. Lois, pp 663–675Google Scholar
  6. 6.
    Hatemi G, Silman A, Bang D, Bodaghi B, Chamberlain A, Gul A, Houman MH, Kötter I, Olivieri I, Salvarani C, Sfikakis PP, Siva A, Stanford MR, Stübiger N, Yurdakul S, Yazici H, EULAR Expert Committee (2008) EULAR recommendations for the management of Behçet disease. Ann Rheum Dis 67:1656–1662CrossRefGoogle Scholar
  7. 7.
    Davatchi F, Assaad-Khalil S, Calamia K, Crook J, Sadeghi-Abdollahi B, Schirmer M et al (2014) The international criteria for Behçet’s disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 28:338–347CrossRefGoogle Scholar
  8. 8.
    Yurdakul S, Hamuryudan V, Yazici H (2004) Behçet syndrome. Curr Opin Rheumatol 16:38–42CrossRefGoogle Scholar
  9. 9.
    Kitaichi N, Miyazaki A, Iwata D, Ohno S, Stanford MR, Chams H (2007) Ocular features of Behçet’s disease: an international collaborative study. Br J Ophthalmol 91:1579–1582CrossRefGoogle Scholar
  10. 10.
    Tugal-Tutkun I, Onal S, Altan-Yaycioglu R, Altunbas HH, Urgancioglu M (2004) Uveitis in Behçet disease: an analysis of 880 patients. Am J Ophthalmol 138:373–380CrossRefGoogle Scholar
  11. 11.
    Choudhary MM, Hajj-Ali RA, Lowder CY (2014) Gender and ocular manifestations of connective tissue diseases and systemic vasculitides. J Ophthalmol 403042.  https://doi.org/10.1155/2014/403042
  12. 12.
    Ucar-Comlekoglu D, Fox A, Sen HN (2014) Gender differences in Behçet’s disease associated uveitis. J Ophthalmol 820710.  https://doi.org/10.1155/2014/820710
  13. 13.
    Tursen U, Gurler A, Boyvat A (2003) Evaluation of clinical findings according to sex in 2313 Turkish patients with Behçet’s disease. Int J Dermatol 42:346–351CrossRefGoogle Scholar
  14. 14.
    Shimizu T, Tanaka I, Ogino K (1970) Current status of Behpet’s disease in Japan. Igaku no Ayumt 75:332–341Google Scholar

Copyright information

© Royal Academy of Medicine in Ireland 2018

Authors and Affiliations

  • Oguz Abdullah Uyaroglu
    • 1
    Email author
  • Emrah Seyhoglu
    • 1
  • Abdulsamet Erden
    • 2
  • Cevanşir Vahabov
    • 1
  • Hakan Babaoglu
    • 1
  • Berkan Armagan
    • 2
  • Alper Sari
    • 2
  • Levent Kilic
    • 2
  • Olcay Tatar
    • 3
  • Sule Apras Bilgen
    • 2
  • Omer Karadag
    • 2
  • Umut Kalyoncu
    • 2
  1. 1.Department of Internal MedicineHacettepe University Faculty of MedicineAnkaraTurkey
  2. 2.Department of Internal Medicine, Division of RheumatologyHacettepe University Faculty of MedicineAnkaraTurkey
  3. 3.Department of OphthalmologyHacettepe University Faculty of MedicineAnkaraTurkey

Personalised recommendations