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Prevalence of sarcopenia in patients with geriatric depression diagnosis

  • Hülya Olgun YazarEmail author
  • Tamer Yazar
Original Article
  • 26 Downloads

Abstract

Aim

In this study, the aim was to identify the prevalence of sarcopenia among patients with geriatric depression (GD) diagnosis and to collect data to illuminate precautions to reduce disease load.

Method

The study was completed with 116 patients (GD group) aged 65 years or older with possible or definite depression diagnosis according to the Geriatric Depression Scale (GDS) criteria and 301 volunteers aged from 18 to 39 years (control 1) and above 65 years (control 2). Our prospective and cross-sectional study applied the Hamilton Depression Rating Scale (HDRS) to control 1 group and the GDS and Mini Mental Test (MMSE) to control 2 and GD groups. All groups had skeletal muscle mass index (SMMI), muscle strength, and physical performance assessed with sarcopenia diagnosis according to the European Working Group on Sarcopenia in Older People (EWGSOP) diagnostic criteria.

Results

In our study, in parallel with the severity of disease in patients with GD diagnosis, the prevalence of sarcopenia (led by severe sarcopenia) was observed to be high compared to the control group. The prevalence of sarcopenia was 12.7%/24.2% among women and 13.8%/44.0% among men and 13.4%/32.8% in total in the control 2 and GD groups, respectively. There was a significant increase observed in the prevalence of sarcopenia, led by severe sarcopenia with a definite depression diagnosis.

Conclusion

For GD patients, diagnosis of sarcopenia in the early stages and precautions like improving muscle functions with protein support in diet and resistance exercises will make it possible to contribute to improving clinical results of the disease.

Keywords

4-m walking test Geriatric depression Hand grip test Sarcopenia Skeletal muscle mass index 

Notes

Authors’ contribution

All authors contributed to writing the manuscript. All authors read and approved the final manuscript.

Compliance with ethical standards

To complete this study with the aim of determining the prevalence of sarcopenia among GD patients monitored at Ordu University Education and Research Hospital and Ordu State Hospital neurology clinics, permission was obtained from General secretary of Ordu Provincial Union of Public Hospitals and Ordu University Education and Research Hospital ethics committee with 2018/85 decision number. Participation in the research was on a voluntary basis, with no names written on data collection forms. Patients and patient relatives were informed that information collected would not be used apart from the aims of the research. Written informed consent was obtained from all participants included in the study.

Conflict of interest

The authors declare that they have no competing interest.

Ethical approval

The authors would like to thank to Dr. Yeliz KAŞKO ARICI (Bioistatistics and Medical Informatics Unit, Faculty of Medicine, Ordu University) for her help with the stastistical analyses of this manuscript.

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Copyright information

© Royal Academy of Medicine in Ireland 2019

Authors and Affiliations

  1. 1.NeurologyOrdu University Education and Research HospitalOrduTurkey
  2. 2.NeurologyOrdu State HospitalOrduTurkey

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