Irish Journal of Medical Science (1971 -)

, Volume 184, Issue 2, pp 435–440

An audit of drug shortages in a community pharmacy practice

  • E. M. Costelloe
  • M. Guinane
  • F. Nugent
  • O. Halley
  • C. Parsons
Original Article



There are no firm data on drug shortages in Irish community pharmacy. This prospective observational study aimed to characterise the drug shortage problem in an Irish community pharmacy.


The primary aim was to determine numbers and durations of drug shortages. Secondary aims included comparing these shortages with Irish Pharmacy Union (IPU) drug shortage lists and determining the frequency with which notifications were received prior to shortages. Further secondary aims were to examine relationships between causes of drug shortages and drug costs and between causes of drug shortages and shortage durations.


The study took place in a community pharmacy in a Limerick City suburb between October 2012 and February 2013. Data were collected daily regarding drugs that were dispensed, but unavailable to purchase. Suppliers/manufacturers provided data on the reasons for shortages.


65/1,232 dispensed drugs (5.3 %) were in short supply over the study period. Median shortage duration was 13 days (interquartile range 4–32 days) and median cost was €8.10. Numbers of unavailable drugs by month varied from 13 to 38. Monthly IPU drug shortage lists identified between six and eight of these shortages depending on the month. Two notifications were received from suppliers/manufacturers regarding shortages. Parallel exports had the highest mean costs (mean €38.05) and manufacturing problems were associated with the longest durations (mean 57.44 days).


This study highlights the drug shortage problem in an Irish community pharmacy. We propose that enhanced communication between all stakeholders is the most worthwhile solution. Further studies are needed.


Community pharmacy Drug shortages Medication risk Patient safety Prescribed medicines Dispensing 


  1. 1.
    Gray A, Manasse HR Jr (2012) Shortages of medicines: a complex global challenge. Bull World Health Organ 90(3):158CrossRefPubMedCentralPubMedGoogle Scholar
  2. 2.
    All_Party_Pharmacy_Group (2012) Report of the APPG inquiry into medicines shortages. Accessed 13 Mar 2014
  3. 3.
    Chemist + Druggist (2013). Medicines shortages 2013. Accessed 13 Mar 2014
  4. 4.
    Drug shortages in hospital pharmacies (2014). Accessed 13 Mar 2014
  5. 5.
    Gatesman MLTJ, Smith TJ (2011) The shortage of essential chemotherapy drugs in the United States. N Engl J Med 365(18):1653–1655CrossRefPubMedGoogle Scholar
  6. 6.
    Ventola CL (2011) The drug shortage crisis in the United States: causes, impact, and management strategies. Phys Ther 36(11):740–757Google Scholar
  7. 7.
    Chabner BA (2011) Drug shortages—a critical challenge for the generic-drug market. N Engl J Med 365(23):2147–2149CrossRefPubMedGoogle Scholar
  8. 8.
    Link MP, Hagerty K, Kantarjian HM (2012) Chemotherapy drug shortages in the United States: genesis and potential solutions. J Clin Oncol 30(7):692–694CrossRefPubMedGoogle Scholar
  9. 9.
    United_States_Food_and_Drug_Administration (2013). Accessed 1 Oct 2013
  10. 10.
    Morrison A (2011) Drug supply disruptions. Canadian Agency for Drugs and Technologies in Health, OttawaGoogle Scholar
  11. 11.
    Huys IS, Simoens (2013) European drug shortages: a call for action! Int J Pharm Pract 21(1):1–2CrossRefPubMedGoogle Scholar
  12. 12.
    Finnegan G (2012) Pharmacists across Europe facing drug shortages. Ir Pharm 14(11):18Google Scholar
  13. 13.
    European_Commission (2001) Directive 2001/83/ec of the European parliament and of the council. Available from: Accessed 7 Jan 2014
  14. 14.
    Irish_Pharmacy_Union (2013) Submission to the Department of Health on Medicines Shortages and Unlicensed Medicines. Accessed 1 Oct 2013
  15. 15.
    Stone P, Curtis SJ (2002) Pharmacy practice, 3rd edn. Pharmaceutical Press, LondonGoogle Scholar
  16. 16.
    Irish_Pharmacy_Union (2014) IPU Product File. Accessed 13 Mar 2014
  17. 17.
    Farmanco (2014) Farmanco. Accessed 1 Mar 2014

Copyright information

© Royal Academy of Medicine in Ireland 2014

Authors and Affiliations

  • E. M. Costelloe
    • 1
    • 2
  • M. Guinane
    • 1
  • F. Nugent
    • 3
  • O. Halley
    • 1
  • C. Parsons
    • 2
  1. 1.Newtown PharmacyLimerickIreland
  2. 2.School of PharmacyQueen’s University BelfastBelfastIreland
  3. 3.Sam McCauley’s PharmacyCorkIreland

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