Irish Journal of Medical Science

, Volume 178, Issue 2, pp 129–134 | Cite as

Preconditioning and its clinical potential

  • P. Magill
  • T. Murphy
  • D. J. Bouchier-Hayes
  • K. J. Mulhall
Review Article


Preconditioning is emerging as a simple, safe and highly effective means of attenuating local and systemic effects of medical and surgical insult. Its enormous potential has not yet been harnessed and ongoing work will continue to bring it to the fore. This article covers the history, development and future clinical potential of preconditioning with particular regard to surgical insult.


Preconditioning Ischaemia–reperfusion injury Remote Delayed Surgical insult 


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Copyright information

© Royal Academy of Medicine in Ireland 2009

Authors and Affiliations

  • P. Magill
    • 1
  • T. Murphy
    • 1
  • D. J. Bouchier-Hayes
    • 2
  • K. J. Mulhall
    • 3
  1. 1.Clinical Research UnitUniversity College DublinDublinIreland
  2. 2.Royal College of Surgeons of IrelandDublinIreland
  3. 3.Cappagh National Orthopaedic HospitalDublinIreland

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