Irish Journal of Medical Science

, Volume 181, Issue 2, pp 273–276 | Cite as

Synchronous sigmoid and caecal cancers together with a primary renal cell carcinoma

  • A. Bhargava
  • M. O’Callaghan
  • T. Abdelhafiz
  • P. Downey
  • A. Nasr
  • S. Nibhraonain
  • C. Davenport
  • M. G. Donovan
  • P. Keeling
Case Report

Abstract

Background

Multiple primary neoplasms, a common clinical entity, can be classified as synchronous or metachronous. Renal cell carcinoma, in particular, is associated with a high rate of multiple primary neoplasms.

Methods

We report a case of a 67-year-old Caucasian woman, who was admitted with history of bleeding per rectum. We conducted a literature review of metachronous and synchronous multiple primary neoplasms.

Results

Colonoscopy revealed a 3 cm tumour in the caecum and a small sigmoid tubulovillous polyp. Staging computed tomography showed a non-enhancing mass in the upper pole of the right kidney. Following a radical nephrectomy/right hemicolectomy, microscopy demonstrated a renal cell carcinoma. Follow-up colonoscopy visualised a mucosal irregularity at the site of the previous sigmoid polyp, with biopsies confirming invasive adenocarcinoma. Patient underwent a total colectomy with an ileo-rectal anastamosis.

Conclusion

Multiple primary neoplasms are a well-recognised clinical entity. This report emphasises the need for a comprehensive evidence-based work-up in all cancer cases, especially when dealing with renal cell carcinoma, to look for coexisting metachronous/synchronous primary neoplasms.

Keywords

Multiple primary neoplasms Renal cell carcinoma Sigmoid adenocarcinoma Caecal adenocarcinoma Synchronous neoplasms Metachronous neoplasms Polyps 

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Copyright information

© Royal Academy of Medicine in Ireland 2009

Authors and Affiliations

  • A. Bhargava
    • 1
    • 6
  • M. O’Callaghan
    • 1
  • T. Abdelhafiz
    • 1
  • P. Downey
    • 2
  • A. Nasr
    • 1
  • S. Nibhraonain
    • 5
  • C. Davenport
    • 4
  • M. G. Donovan
    • 3
  • P. Keeling
    • 1
  1. 1.Department of SurgeryConnolly HospitalDublin 15Ireland
  2. 2.Department of PathologyConnolly HospitalDublin 15Ireland
  3. 3.Department of UrologyConnolly HospitalDublin 15Ireland
  4. 4.Department of EndocrinologyBeaumont HospitalDublin 9Ireland
  5. 5.Department of Emergency MedicineBeaumont HospitalDublin 9Ireland
  6. 6.EnfieldUSA

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