Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU
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The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality.
To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants.
The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid–base balance in 24-h intervals during the first 28 days of life.
A NEOMOD of ≥9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality.
The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.
KeywordsMortality Multiple organ dysfunction Preterm newborn Scoring system
- 1.Deitch EA (1992) Multiple organ failure (pathophysiology and potential future therapy). Ann Surg 8:117–134Google Scholar
- 4.John RCS, Dorinsky PM (1994) An overview of a multiple organ dysfunction syndrome. J Lab Clin Med 10:478–448Google Scholar
- 16.Richardson DK, Tarnow-Mordi WO (1994) Measuring illness severity in newborn intensive care. J Intensive Care Med 9:20–33Google Scholar
- 17.Leteurtre S, Martinot A, Duhamel A, Proulx F, Grandbastien B, Cotting J, Gottesman R, Joffe A, Pfenninger J, Hubert P, Lacroix J, Leclerc F (2003) Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study. Lancet 362(9379):192–197PubMedCrossRefGoogle Scholar