Advertisement

Ameloblastom

Einordnung gemäß der aktuellen WHO-Klassifikation
  • D. SchneiderEmail author
  • P. W. Kämmerer
CME Zahnärztliche Fortbildung
  • 1 Downloads

Zusammenfassung

Das Ameloblastom ist ein lokal invasiver odontogener Tumor mit verschiedenen histologischen Varianten und hoher Rezidivrate. Es gehört neben dem Odontom und der Keratozyste zu den häufigsten vorkommenden odontogenen Neoplasien. Die Therapie des Ameloblastoms besteht in der Resektion mit geeignetem Sicherheitsabstand. Zu Beginn des Jahres 2017 wurde die 4. und aktuelle Auflage der WHO-Klassifikation für Kopf-Hals-Tumoren publiziert. Sie überraschte allerdings mit zahlreichen Rerevisionen der Einordnungen aus der 3. Version.

Schlüsselwörter

Kieferneoplasien Odontogene Tumoren Zahnschmelz Humanes BRAF-Protein Kopf-Hals-Tumoren 

Notes

Einhaltung ethischer Richtlinien

Interessenkonflikt

D. Schneider und P.W. Kämmerer geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

Literatur

  1. 1.
    McClary AC et al (2016) Ameloblastoma: A clinical review and trends in management. Eur Arch Otorhinolaryngol 273(7):1649–1661CrossRefGoogle Scholar
  2. 2.
    Sweeney RT et al (2014) Identification of recurrent SMO and BRAF mutations in ameloblastomas. Nat Genet 46(7):722–725CrossRefGoogle Scholar
  3. 3.
    Wright JM, Vered M (2017) Update from the 4th edition of the World Health Organization classification of head and neck tumours: Odontogenic and maxillofacial bone tumors. Head Neck Pathol 11(1):68–77CrossRefGoogle Scholar
  4. 4.
    Wright JM, Soluk Tekkeşin M (2017) Odontogenic tumors: Where are we in 2017? J Istanb Univ Fac Dent 51(3 Suppl 1):S10–S30PubMedPubMedCentralGoogle Scholar
  5. 5.
    Vered M, Muller S, Heikinheimo K (2017) Ameloblastoma. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Hrsg) WHO classification of head and neck tumours, 4. Aufl. WHO classification of tumours, Bd. 9. IARC Press, Lyon, S 215–218Google Scholar
  6. 6.
    Gardner DG, Heikinheimo K, Shear M, Philipsen HP, Coleman H (2005) Ameloblastomas. In: Barnes L, Eveson JW, Reichart P, Sidransky D (Hrsg) Pathology and genetics, head and neck tumors, 3. Aufl. WHO classification of tumours, Bd. 9. IARC Press, Lyon, S 296–300Google Scholar
  7. 7.
    Speight PM, Takata T (2018) New tumour entities in the 4th edition of the World Health Organization classification of head and neck tumours: Odontogenic and maxillofacial bone tumours. Virchows Arch 472(3):331–339CrossRefGoogle Scholar
  8. 8.
    Baumhoer D (2018) Odontogenic tumours and bone tumours of the jaw: Changes in the new WHO classification. Pathologe 39(1):35–41CrossRefGoogle Scholar
  9. 9.
    Cusack JW (1827) Report of the amputations of the lower jaw. Dublin Hosp Rec 4:1–38Google Scholar
  10. 10.
    Ivey RH, Churchill HR (1930) The need of a standardized surgical and pathological classification of tumors and anomalies of dental origin. Am Assoc Dent Sch Trans 7:240–245Google Scholar
  11. 11.
    Brazis PW et al (1995) Neuro-ophthalmologic aspects of ameloblastoma. Skull Base Surg 5(4):233–244CrossRefGoogle Scholar
  12. 12.
    Lu Y et al (1998) Odontogenic tumors. A demographic study of 759 cases in a Chinese population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86(6):707–714CrossRefGoogle Scholar
  13. 13.
    Mosadomi A (1975) Odontogenic tumors in an African population. Analysis of twenty-nine cases seen over a 5-year period. Oral Surg Oral Med Oral Pathol 40(4):502–521CrossRefGoogle Scholar
  14. 14.
    Daley TD, Wysocki GP, Pringle GA (1994) Relative incidence of odontogenic tumors and oral and jaw cysts in a Canadian population. Oral Surg Oral Med Oral Pathol 77(3):276–280CrossRefGoogle Scholar
  15. 15.
    Regezi JA, Kerr DA, Courtney RM (1978) Odontogenic tumors: Analysis of 706 cases. J Oral Surg 36(10):771–778PubMedGoogle Scholar
  16. 16.
    Kämmerer PW et al (2016) Clinical parameter of odontoma with special emphasis on treatment of impacted teeth—A retrospective multicentre study and literature review. Clin Oral Investig 20(7):1827–1835CrossRefGoogle Scholar
  17. 17.
    Larsson A, Almerén H (1978) Ameloblastoma of the jaws. An analysis of a consecutive series of all cases reported to the Swedish Cancer Registry during 1958–1971. Acta Pathol Microbiol Scand A 86:337–349.  https://doi.org/10.1111/j.1699-0463.1978.tb02054.x CrossRefGoogle Scholar
  18. 18.
    Reichart PA, Philipsen HP, Sonner S (1995) Ameloblastoma: Biological profile of 3677 cases. Eur J Cancer, B, Oral Oncol 31(2):86–99CrossRefGoogle Scholar
  19. 19.
    Schafer DR et al (1998) Primary ameloblastoma of the sinonasal tract: A clinicopathologic study of 24 cases. Cancer 82(4):667–674CrossRefGoogle Scholar
  20. 20.
    Becelli R et al (2002) Mandibular ameloblastoma: Analysis of surgical treatment carried out in 60 patients between 1977 and 1998. J Craniofac Surg 13(3):395–400 (discussion 400)CrossRefGoogle Scholar
  21. 21.
    Stanley HR, Diehl DL (1965) Ameloblastoma potential of follicular cysts. Oral Surg Oral Med Oral Pathol 20:260–268CrossRefGoogle Scholar
  22. 22.
    Buchner A, Merrell PW, Carpenter WM (2006) Relative frequency of central odontogenic tumors: A study of 1,088 cases from Northern California and comparison to studies from other parts of the world. J Oral Maxillofac Surg 64(9):1343–1352CrossRefGoogle Scholar
  23. 23.
    Philipsen HP, Reichart PA (1998) Unicystic ameloblastoma. A review of 193 cases from the literature. Oral Oncol 34(5):317–325CrossRefGoogle Scholar
  24. 24.
    Philipsen HP, Reichart PA, Takata T (2001) Desmoplastic ameloblastoma (including “hybrid” lesion of ameloblastoma). Biological profile based on 100 cases from the literature and own files. Oral Oncol 37(5):455–460CrossRefGoogle Scholar
  25. 25.
    Dissanayake RK et al (2011) Review of metastasizing (malignant) ameloblastoma (METAM): Pattern of metastasis and treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111(6):734–741CrossRefGoogle Scholar
  26. 26.
    Van Dam SD, Unni KK, Keller EE (2010) Metastasizing (malignant) ameloblastoma: Review of a unique histopathologic entity and report of Mayo Clinic experience. J Oral Maxillofac Surg 68(12):2962–2974CrossRefGoogle Scholar
  27. 27.
    Chai Y et al (2000) Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development 127(8):1671–1679PubMedGoogle Scholar
  28. 28.
    Hertog D et al (2012) Histopathology of ameloblastoma of the jaws; some critical observations based on a 40 years single institution experience. Med Oral Patol Oral Cir Bucal 17(1):e76–e82CrossRefGoogle Scholar
  29. 29.
    Carlson ER, Marx RE (2006) The ameloblastoma: Primary, curative surgical management. J Oral Maxillofac Surg 64(3):484–494CrossRefGoogle Scholar
  30. 30.
    Sham E et al (2009) Mandibular ameloblastoma: Clinical experience and literature review. Anz J Surg 79(10):739–744CrossRefGoogle Scholar
  31. 31.
    Becelli R et al (2011) Treatment of recurrent mandibular ameloblastoma with segmental resection and revascularized fibula free flap. J Craniofac Surg 22(3):1163–1165CrossRefGoogle Scholar
  32. 32.
    Hertog D, van der Waal I (2010) Ameloblastoma of the jaws: A critical reappraisal based on a 40-years single institution experience. Oral Oncol 46(1):61–64CrossRefGoogle Scholar
  33. 33.
    Olaitan AA, Adeola DS, Adekeye EO (1993) Ameloblastoma: Clinical features and management of 315 cases from Kaduna, Nigeria. J Craniomaxillofac Surg 21(8):351–355CrossRefGoogle Scholar
  34. 34.
    Müller H, Slootweg PJ (1985) The ameloblastoma, the controversial approach to therapy. J Maxillofac Surg 13(2):79–84CrossRefGoogle Scholar
  35. 35.
    Eckardt AM et al (2009) Recurrent ameloblastoma following osseous reconstruction—A review of twenty years. J Craniomaxillofac Surg 37(1):36–41CrossRefGoogle Scholar
  36. 36.
    Nakamura N et al (2002) Comparison of long-term results between different approaches to ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93(1):13–20CrossRefGoogle Scholar

Copyright information

© Freier Verband Deutscher Zahnärzte (FVDZ) and Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2019

Authors and Affiliations

  1. 1.Klinik für Mund‑, Kiefer- und Plastische GesichtschirurgieHelios Kliniken SchwerinSchwerinDeutschland
  2. 2.Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie der Universitätsmedizin MainzMainzDeutschland

Personalised recommendations