Antimicrobial properties of silver-doped hydroxyapatite nano-powders and thin films
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Silver-doped hydroxyapatite nanopowders were prepared using a solution based sol-gel method and thoroughly characterized using x-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). Antibacterial tests showed silver-doped HAP powders prevented the growth and reproduction of bacteria. Silver-doped HAP powders were pressed into pellets and on these pellets a pulsed laser deposition (PLD) technique was employed to grow amorphous and crystalline thin films on sapphire substrates. Crystalline films had silver nano-particles present within the HAP matrix. Film stability tests showed crystalline films to be far more stable in prolonged solution submersion than their amorphous counterparts.
KeywordsScanning Electron Microscopy Thin Film Hydroxyapatite Sapphire Energy Dispersive Spectroscopy
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- 2.A.D. Hanssen and J.A. Rand, “Evaluation and Treatment of Infection at the Site of a Total Hip or Knee Arthroplasty? J. Bone Joint Surg., 80A (1998), pp. 910–922.Google Scholar
- 4.R.J. Narayan, “DLC/Hydroxyapatite Nanocomposites,” Mat. Res. Soc. Symp. Proc. 795 (2004), pp. U12.9.1–U12.9.6.Google Scholar
- 8.H.C. Wu et al., “A Novel Biomagnetic Nanoparticle Based on Hydroxyapatite,” Nanotechnology, 18 (2007), pp. 1–9.Google Scholar
- 14.M. Sygnatowicz and A. Tiwari, “Controlled Synthesis of Hydroxyapatite-based Coatings for Biomedical Application,” Mater. Sci. Eng. C (2008) doi:1016/j.msec.2008.08.036.Google Scholar
- 29.B.D. Cullity and S.R. Stock, Elements of X-Ray Diffraction. 3rd ed. (Upper Saddle River, NJ: Prentice Hall, 2001).Google Scholar
- 30.B. Viswanath et al., “Sintering and Microstructural Characterization of Nanocrystalline Hydroxyapatite Composites,” Mater. Res. Soc. Symp. Proc. 845 (2005), pp.AA5.31.1–AA5.31.6.Google Scholar