Mund und Maskenleckage bei Kontrolluntersuchungen
- 55 Downloads
Zusammenfassung
Unter Applikation von nasalem Überdruck (CPAP) wird normalerweise eine ventrale Velagerung des weichen Gaumens erreicht, hierdurch entwickelt sich ein Verschluss des Oropharynx zur Mundhöhle hin und in der Mundhöhle ist der Überdruck nicht wirksam. Dieser Verschluss wird auch soft palat seal bezeichnet. Aus verschiedenen Gründen kann dieser Verschluss jedoch unvollständig sein und Patienten können Mundatmung unter nasalem CPAP entwickeln. Beim Auftreten einer hinreichend großen Mundleckage kann kein suffizienter Therapiedruck zur Vermeidung des oropharyngealen Kollapses aufgebaut werden. Dies begünstigt zusätzlich Mundatmung.
Leckagen infolge Mundatmung unter CPAP führen zu einem erhöhten Flow des Therapiegerätes, um den Druck konstant zu halten. Der erhöhte Luftfluss führt zu den bekannten Nebenwirkungen wie Trockenheit an den Nasen- und Rachenschleimhäuten. Konsekutiv schwellen die Nasenschleimhäute an und es resultiert ein höherer Fluss-Widerstand in der Nase. Dies führt zu einem weiteren Abfall des effektiven Therapiedrucks im Oropharynx.
Subjektiv fühlen die Patienten sich durch die Rhinitis gestört. Eine verringerte Compliance oder gar Inakzeptanz von CPAP können die Folge sein.
Es liegen nur wenige Untersuchungen zum Effekt von Kontrolluntersuchungen bei Mund- und Masken-Leckagen vor. In den vorliegenden Studien wird ein Evidenzgrad besser als 4 nicht erreicht. In einer Vergleichsstudie zeigten Patienten mit Mundatmung über 70 Prozent der Gesamtschlafzeit im Verlauf eine geringere Compliance als Patienten mit einer geringen Mundatmung. Damit liegen erste Daten vor, die auf die Bedeutung von Mundleckagen hinweisen. Bei verminderter Compliance sollten Kontrolluntersuchungen neben den Nasen-Rachen-Beschwerden die Leckagedaten der Geräte berücksichtigen.
Schlüsselwörter
OSAS CPAP Nebenwirkungen Masken LeckageMouth breathing and mask leakage during check-ups
Summary
During the application of nasal continuous positive airway pressure (CPAP), the velum is normally shifted in the ventral direction and an occlusion of the oropharynx against the oral cavity results. Therefore, positive airway pressure is not effective in the oral cavity. This occlusion is also called soft palatal seal. Due to different reasons; however, the occlusion can be incomplete and therefore patients can develop mouth breathing under nasal CPAP.
Beyond a certain threshold of mouth leakage, which varies individually, the CPAP device Is no longer capable of building up enough pressure to avoid oropharyngeal collapsing. This also promotes oral breathing under nasal CPAP. Leakage due to oral breathing leads to a higher flow of the CPAP machine in order to maintain the pressure. The amplified airflow leads to known adverse effects, such as dryness of nasal and oral mucosa. Consecutively blood flow in nasal mucosa increases and nasal obstruction worsens, leading to further reduction of the effective therapy pressure in the oropharynx. The patients feel disturbed by the rhinitis, and lower compliance or a total refusal of CPAP can be the consequence.
There are only scarse studies trials on the effect of follow-up examinations with regard to the effect of mouth breathing and mask leakages. In these trials no level of evidence better than 4 is reached. In a comparative study, patients with mouth breathing during more than 70 % of the entire sleeping time showed lower compliance than patients with less mouth breathing. This study is suggestive of the negative effect of mouth breathing on the compliance of CPAP. Therefore, when insufficient compliance is uncovered, check-ups should quantify the mucosa side effects and the leakage data from the CPAP machine.
Key words
OSAS CPAP adverse effects masks leakagePreview
Unable to display preview. Download preview PDF.
Literatur
- 1.Lindberg E, Berne C, Elmasry A, Hedner J, Janson C (2006) CPAP treatment of a population ñbased sample-what are the benefits and the treatment compliance? Sleep Medicine 7:553–560PubMedCrossRefGoogle Scholar
- 2.Kribbs NB, Pack AI, Kline LR, Smith PL, Schwartz A, Schubert N, Redline S, Henry JN, Getsy JE, Dings DF (1993) Objective measurement of patterns of nasal CPAP use by patients with obstructive sleep apnea. Am Rev Respir Dis 147:887–895PubMedGoogle Scholar
- 3.Sin DD, Mayers I, Man GC, et al. (2002) Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea. Chest 121:430–435PubMedCrossRefGoogle Scholar
- 4.Kasai T, Narui K, Dohi T, Yanagisawa N, Ishiwata S, Ohno M, Yamaguchi T, Momomura S (2008) Prognosis of patients with heart failure and obstructive sleep apnea treated with continuous positive airway pressure. Chest 133:690–696PubMedCrossRefGoogle Scholar
- 5.Milleron O, Pillière R, Foucher A, de Roquefeuil F, Aegerter P, Jondeau G, Raffestin BG, Dubourg O (2004) Benefits of obstructive sleep apnoea treatment in coronary artery disease: a long-term follow-up study. Eur Heart J 25:709–711CrossRefGoogle Scholar
- 6.Marin JM, Carrizo SJ, Vicente E, Agusti AG (2005) Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 365:1046–1053PubMedGoogle Scholar
- 7.Buchner NJ, Sanner BM, Borgel J, Rump LC (2007) Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk. Am J Respir Crit Care Med 176:1274–1280PubMedCrossRefGoogle Scholar
- 8.Campos-Rodriguez F, Perez-Ronchel J, Grilo-Reina A, Lima-Alvarez J, Benitez MA, Almeida-Gonzalez C (2007) Long-term effect of continuous positive airway pressure on BP in patients with hypertension and sleep apnea. Chest 132:1847–1852PubMedCrossRefGoogle Scholar
- 9.Weaver TE, Maislin G, Dinges DF, Bloxham T, George CF, Greenberg H, Kader G, Mahowald M, Younger J, Pack AI (2007) Relationship between hours of CPAP use and achieving normal levels of sleepiness and daily functioning. Sleep 30:711–719PubMedGoogle Scholar
- 10.George CF (2001) Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP. Thorax 56:508–512PubMedCrossRefGoogle Scholar
- 11.Gay P, Weaver T, Loube D, Iber C (2006) Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Sleep29:381–401PubMedGoogle Scholar
- 12.Budhiraja R, Parthasarathy S, Drake CL, Roth T, Sharief I, Budhiraja P, Saunders V, Hudgel DW (2007) Early CPAP use identifies subsequent adherence to CPAP therapy. Sleep 30:320–324PubMedGoogle Scholar
- 13.McArdle N, Devereux G, Heidarnejad H, Engleman HM, Mackay TW, Douglas NJ (1999) Long-term use of CPAP therapy for sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med 159:1108–1114PubMedGoogle Scholar
- 14.Barbe F, Mayoralas LR, Duran J, Masa JF, Maimo A, Montserrat JM, Monasterio C, Bosch M, Ladaria A, Rubio M, et al. (2001) Treatment with continuous positive airway pressure is not effective in patients with sleep apnea but no daytime sleepiness. a randomized, controlled trial. Ann Intern Med 134:1015–1023PubMedGoogle Scholar
- 15.Drake CL, Day R, Hudgel D, et al. (2003) Sleep during titration predicts continuous positive airway pressure compliance. Sleep 26:308–311PubMedGoogle Scholar
- 16.Kjelsberg FN, Ruud EA, Stavem K (2005) Predictors of symptoms of anxiety and depression in obstructive sleep apnea. Sleep Med 6:341–346PubMedCrossRefGoogle Scholar
- 17.Chasens ER, Pack AI, Maislin G, Dinges DF, Weaver TE (2005) Claustrophobia and adherence to CPAP treatment. West J Nurs Res 27:307–321PubMedCrossRefGoogle Scholar
- 18.Lewis KE, Seale L, Bartle IE, et al. (2004) Early predictors of CPAP use for the treatment of obstructive sleep apnea. Sleep 27:134–138PubMedGoogle Scholar
- 19.Haniffa M, Lasserson TJ, Smith I (2004) Interventions to improve compliance with continuous positive airway pressure for obstructive sleep apnoea. Cochrane Database Syst Rev 4:CD003531Google Scholar
- 20.Chervin RD, Theut S, Bassetti C, Aldrich MS (1997) Compliance with nasal CPAP can be improved by simple interventions. Sleep 20:284–289PubMedGoogle Scholar
- 21.Jean Wiese H, Boethel C, Phillips B, Wilson JF, Peters J, Viggiano T (2005) CPAP compliance: video education may help! Sleep Med 6:171–174PubMedCrossRefGoogle Scholar
- 22.Likar LL, Panciera TM, Erickson AD, Rounds S (1997) Group education sessions and compliance with nasal CPAP therapy. Chest 111:1273–1277PubMedCrossRefGoogle Scholar
- 23.Hoffstein V, Viner S, Mateika S, Conway J (1992) Treatment of obstructive sleep apnea with nasal continuous positive airway pressure: patient compliance, perception of benefits, and side effects. Am Rev Respir Dis 145:841–845PubMedGoogle Scholar
- 24.Englemann HM, Asgari-Jirhandeh N, McLeod AL, et al. (1996) Self-Reported Use of CPAP and Benefits of CPAP Therapy Chest 109:1470–1476CrossRefGoogle Scholar
- 25.Hayes MJ, McGregor FB, Roberts DN, et al. (1995) Continuous nasal positive airway pressure with a mouth leak: effect on nasal mucosal blood flux and nasal geometry. Thorax 50:179–182Google Scholar
- 26.Richards GN, Cistulli PA, Ungar G, et al. (1996) Mouth Leak With Nasal Continuous Positive Airway Pressure Increases Nasal Airway Resistance. Am J Respir Crit Care Med 154:182–186PubMedGoogle Scholar
Literaturstellen der systematischen Literatursuche
- 27.Richter HE, Burgio KL, Clements RH, Goode PS, Redden DT, Varner RE (2005) Urinary and anal incontinence in morbidly obese women considering weight loss surgery. Obstet Gynecol 106:1272–1277PubMedGoogle Scholar
- 28.Mattioli G, Castagnetti M, Martucciello G, Jasonni V (2004) Results of a mechanical Duhamel pull-through for the treatment of Hirschsprung‘s disease and intestinal neuronal dysplasia. J Pediatr Surg 39:1349–1355PubMedCrossRefGoogle Scholar
- 29.Bliwise DL, Adelman CL, Ouslander JG (2004) Polysomnographic correlates of spontaneous nocturnal wetness episodes in incontinent geriatric patients. Sleep 27:153–157PubMedGoogle Scholar
- 30.Ceelen W, Walder J, Cardon A, Van Renterghem K, Hesse U, El Malt M, Pattyn P (2003) Surgical treatment of severe obesity with a low-pressure adjustable gastric band: experimental data and clinical results in 625 patients. Ann Surg 237:10–16PubMedCrossRefGoogle Scholar
- 31.Hill NS, Carlisle C, Kramer NR (2002) Effect of a nonrebreathing exhalation valve on long-term nasal ventilation using a bilevel device. Chest 122:84–91PubMedCrossRefGoogle Scholar
- 32.Huerta S, DeShields S, Shpiner R, Li Z, Liu C, Sawicki M, Arteaga J, Livingston EH (2002) Safety and efficacy of postoperative continuous positive airw y pressure to prevent pulmonary complications after Roux-en-Y gastric bypass. J Gastrointest Surg 6:354–358PubMedCrossRefGoogle Scholar
- 33.Jaghagen EL, Berggren D, Isberg A (2000) Swallowing dysfunction related to snoring: a videoradiographic study. Acta Otolaryngol 120:438–443PubMedCrossRefGoogle Scholar
- 34.Isberg A, Levring-Jaghagen E, Dahlstrom M, Dahlqvist A (1998) Persistent dysphagia after laser uvulopalatoplasty: a videoradiographic study of pharyngeal function. Acta Otolaryngol 118:870–874PubMedCrossRefGoogle Scholar
- 35.Grunstein RR (1995) Sleep-related breathing disorders. 5. Nasal continuous positive airway pressure treatment for obstructive sleep apnoea. Thorax 50:1106–1113PubMedCrossRefGoogle Scholar
- 36.Engum SA, Grosfeld JL, West KW, Rescorla FJ, Scherer LR 3rd (1995) Analysis of morbidity and mortality in 227 cases of esophageal atresia and/or tracheoesophageal fistula over two decades. Arch Surg 130:502–508; discussion 508–509PubMedGoogle Scholar
- 37.Lang M, Schwering MS, Schober JG (1995) Practical experiences with home ventilation in childhood. Med Klin (Munich) 90(1 Suppl 1):52–56Google Scholar
- 38.Becker H, Fett I, Nees E, Peter JH, von Wichert P (1991) Treatment of primary and secondary therapy failure in patients with sleep apnea treated with nasal CPAP. Pneumologie 45(Suppl 1):301–305PubMedGoogle Scholar
- 39.Mesgarzadeh M, Haines JE, Bobba VR, Von Dollen LE, Jarboe G, Krishnamurthy GT (1983) Diagnosis of clinically unsuspected gallbladder perforation in an obesepatient, by Tc-99m IDA cholescintigraphy. J Nucl Med 24:1028–1029PubMedGoogle Scholar
- 40.Bachour A, Maasilta P (2004) Mouth breathing compromises adherence to nasal continuous positive airway pressure therapy. Chest 126:1248–1254PubMedCrossRefGoogle Scholar
- 41.Galetke W, Anduleit N, Richter K, Stieglitz S, Randerath WJ (2008) Comparison of Automatic and Continuous Positive Airway Pressure in a Night-by-Night Analysis: A Randomized, Crossover Study. Respiration 75:163–169PubMedCrossRefGoogle Scholar
- 42.Han F, Song W, Li J, Zhang L, Dong X, He Q (2006) Influence of UPPP surgery on tolerance to subsequent continuous positive airway pressure in patients with OSAHS. Sleep Breath 10:37–42PubMedCrossRefGoogle Scholar
- 43.Ruhle KH, Randerath W (2000) Measurement of mask leakage during CPAP in patients with obstructive sleep apnea. Pneumologie 54:422–424PubMedCrossRefGoogle Scholar
- 44.Mortimore IL, Whittle AT, Douglas NJ (1998) Comparison of nose and face mask CPAP therapy for sleep apnoea. Thorax 53:290–292PubMedCrossRefGoogle Scholar
- 45.Bachour A, Maasilta P (2004) Mouth breathing compromises adherence to nasal continuous positive airway pressure therapy. Chest 126:1248–1254PubMedCrossRefGoogle Scholar