Korean Journal of Chemical Engineering

, Volume 33, Issue 4, pp 1125–1133 | Cite as

Recent developments and applications of bioinspired silicification

  • Byung Hoon Jo
  • Chang Sup Kim
  • Yun Kee Jo
  • Hogyun Cheong
  • Hyung Joon Cha
Invited Review Paper


Bioinspired synthesis of silica has attracted attention from a wide range of researchers as novel route for fabrication of various nanomaterials. Proteins including silaffins and silicateins as well as polyamines from marine diatoms and sponges are key biomolecules in these biomimetic silicification processes. These methods allow silica mineralization from various silica precursors under mild, biologically compatible conditions in an unprecedentedly fast and facile manner. Notably, the silica polycondensation entails the concomitant encapsulation of other molecules in the reaction solutions. Due to the efficient encapsulation and synergetic effects brought by the encapsulated molecules and the characteristics of biomimetic silica synthesis as well as the mechanical and chemical properties of silica itself, the silica- biomolecule nanocomposites have broad applications in biocatalysis, biosensor, and biomedical areas. Introduction and combination of novel template, precursors, inorganics, or enzymes with the previously used strategies will allow construction of more efficient, purpose-optimized silica nanomaterials with controlled size, composition, and morphology.


Biosilica Biosilicification Silaffin Silicatein Polyamine 


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Copyright information

© Korean Institute of Chemical Engineers, Seoul, Korea 2016

Authors and Affiliations

  • Byung Hoon Jo
    • 1
  • Chang Sup Kim
    • 2
  • Yun Kee Jo
    • 1
  • Hogyun Cheong
    • 1
  • Hyung Joon Cha
    • 1
  1. 1.Department of Chemical EngineeringPohang University of Science and TechnologyPohangKorea
  2. 2.School of Chemistry and BiochemistryYeungnam UniversityGyeongsanKorea

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