Light absorption distribution of uterine tissue filled with strong scattering medium irradiated by diffused light source
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Determining the light absorption distribution (LAD) of uterine tissue helps the detection of endometrial carcinoma. In this work, a 3-dimensional optical model of the human uterus is proposed and examined. The model is filled with strong scattering medium (undiluted raw and homogenized milk, URHM) or air at 630 nm and 800 nm wavelengths. Monte Carlo simulations are used to find the absorption profiles of photons by transcervical laser illumination, with a cylindrically diffused light source (CDLS) or spherically diffused light source (SDLS). The results show that 800 nm is a good laser wavelength value for the detection of endometrial carcinoma by photoacoustic imaging (PAI). At the same time, the shape of the light source becomes less important in a relatively large cavity. The impacts of different scattering coefficients of CDLS on the irradiated area are demonstrated. Strong scattering medium is helpful to the illumination of the uterus cavity.
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- Cancer Council, Understanding Cancer of the Uterus, Cancer Council Australia, 2017.Google Scholar
- American Cancer Society, Cancer Facts & Figures 2017, American Cancer Society, 2017.Google Scholar
- Torre L A, Bray F, Siegel R L, Ferlay J, Lortet-Tieulent J and Jemal A, CA: A Cancer Journal for Clinicians 65, 87 (2015).Google Scholar
- Chen W, Zheng R, Baade P D, Zhang S, Zeng H, Bray F, Jemal A, Yu X Q and He J, CA: A Cancer Journal for Clinicians 66, 115 (2016).Google Scholar
- Daftrey S and Chakravarti S, Manual of Obstetrics, 2014.Google Scholar
- Ren S, Chen X, Wang H, Qu X, Wang G, Liang J and Tian J, ed C M Aegerter PLoS ONE 8, e61304 (2013).Google Scholar