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CRT-Therapie: Strategien zur Vermeidung von Non-respondern

CRT therapy: strategies to avoid “non-responders”

  • Published:
Clinical Research in Cardiology Supplements Aims and scope

Zusammenfassung

Die Zahl der Non-Responder bei einer aufwändigen, teuren CRT-Therapie ist hoch. Nach den vorliegenden Daten kann der Responder schon im Vorfeld charakterisiert werden. Eine Ansprechbarkeit auf die CRT-Therapie ist zu erwarten bei einer deutlichen Verbreiterung des QRS-Komplexes (> 120 ms), dem echokardiographischen Nachweis einer Asynchronie sowie einer nichtischämischen Kardiomyopathie. Der Erfolg ist erst nach ca. 6 Monaten objektivierbar. Veränderungen der Lebensqualität lassen sich durchaus auch früher nachweisen. Die CRT-Therapie ersetzt nicht eine medikamentöse Herzinsuffizienztherapie. Eine Optimierung der medikamentösen Herzinsuffizienztherapie gehört zur CRT-Therapie. Im Verlauf der CRT-Therapie sind die Medikation, die interventionellen Maßnahmen und die Aktualisierung der Programmierung unerlässlich.

Abstract

There are a high number of non-responders in CRT therapy. What is the definition of “responder”? Responding depends on the broadening of the QRS complex (> 120 ms) and the evidence of asynchrony echocardiographically. Success can be evaluated after a 6 month period. CRT should be considered as an additional form of congestive heart failure therapy and requires optimal medical management.

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Authors and Affiliations

  1. Medizinische Klinik 3, St. Vincentius-Kliniken, Südendstraße 32, 76137, Karlsruhe, Germany

    B.-D. Gonska

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  1. B.-D. Gonska
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Correspondence to B.-D. Gonska.

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Gonska, BD. CRT-Therapie: Strategien zur Vermeidung von Non-respondern. Clin Res Cardiol Suppl 4 (Suppl 2), 160–164 (2009). https://doi.org/10.1007/s11789-009-0064-1

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  • DOI: https://doi.org/10.1007/s11789-009-0064-1

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