Synthesis and structural characterization of macroporous bioactive glass

  • Zhou Zhi-hua  (周智华)
  • Ruan Jian-ming  (阮建明)Email author
  • Zou Jian-peng  (邹俭鹏)
  • Zhou Zhong-cheng  (周忠诚)
  • Shen Xiong-jun  (申雄军)


Porous sol-gel glass of CaO-SiO2-P2O5 system with macropores larger than 100 μm was prepared by adding stearic acid as pore former when the sintering was carried out at 700 °C for 3 h. The sol-gel porous glass shows an amorphous structure. The diameter of the pore created by pore former varies from 100 to 300 μm, and macroporous glass has a narrow and small pore size distribution in mesoporous scale. The porosity and pore size of macroporous bioactive glass can be controlled.

Key words

macroporous glass sol-gel method synthesis structural characterization 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. [1]
    HENCH L L. Bioceramics[J]. J Am Ceram Soc, 1998, 81(7): 1705–1728.CrossRefGoogle Scholar
  2. [2]
    OHURA K, NAHAMURA T, KOKUBO T, et al. Bone-bonding ability of P2O5-free CaO-SiO2 glasses[J]. J Biomed Mater Res, 1991, 25(3): 357–365.CrossRefGoogle Scholar
  3. [3]
    ZHONG J P, GREENSPAN D C. Processing and properties of sol-gel bioactive glasses[J]. J Biomed Mater Res, 2000, 53(6): 694–697.CrossRefGoogle Scholar
  4. [4]
    VALLET-REGI M. Ceramics for medical applications[J]. J Chem Soc Dalton Trans, 2001, 17: 97–108.CrossRefGoogle Scholar
  5. [5]
    HENCH L L. Bioceramics: From concept to clinic[J]. J Am Ceram Soc, 1991, 74(7): 1487–1510.CrossRefGoogle Scholar
  6. [6]
    ROMIAN J, PADILLA S, VALLET M. Sol-gel glasses as precursors of bioactive glass ceramics[J]. Chem Mater, 2003, 15(3): 798–806.CrossRefGoogle Scholar
  7. [7]
    PEREIRA M M, CLARK A E, HENCH L L. Calcium phosphate formation on sol-gel-derived bioactive glasses in vitro[J]. J Biomed Mater Res, 1994, 28(6): 693–698.CrossRefGoogle Scholar
  8. [8]
    SEPULVEDA P, JONES J R, HENCH L L. In vitro dissolution of melt-derived 45S5 and sol-gel derived 58S bioactive glasses[J]. J Biomed Mater Res, 2002, 61(2): 301–311.CrossRefGoogle Scholar
  9. [9]
    LIU Jian-li, MIAO Xi-geng. Sol-gel derived bioglass as a coating material for porous alumina scaffolds[J]. Ceramics International, 2004, 30(7): 1781–1785.CrossRefGoogle Scholar
  10. [10]
    JONES J R, AHIR S, HENCH L L. Large-scale production of 3D bioactive glass macroporous scaffolds for tissue engineering[J]. Journal of Sol-Gel Science and Technology, 2004, 29(3): 179–188.CrossRefGoogle Scholar
  11. [11]
    JIE Qing, LIN Kai-li, ZHONG Ji-pin, et al. Preparation of macroporous sol-gel bioglass using PVA particles as pore former[J]. Journal of Sol-Gel Science and Technology, 2004, 30(1): 49–61.CrossRefGoogle Scholar
  12. [12]
    DUVAL C. Inorganic Thermogravimetric Analysis[M]. New York: Elsevier, 1963: 274.Google Scholar
  13. [13]
    HE Feng, LIU Chang-sheng. Preparation of porous glass-ceramic with controlled pore size and porosity by adding porosifier[J]. Journal of Inorganic Materials, 2004, 19(6): 1267–1276.(in Chinese)Google Scholar
  14. [14]
    BRUNAUER S, DEMING L S, DEMING W E, et al. On a theory of the van der Waals adsorption of gases[J]. J Am Chem Soc, 1940, 62: 1723–1732.CrossRefGoogle Scholar
  15. [15]
    SING K S W, EVERETT D H, HAUL R A W, et al. Reporting physisorption data for gas/solid systems[J]. Pure Appl Chem, 1985, 57(4): 603–619.CrossRefGoogle Scholar

Copyright information

© Published by: Central South University Press, Sole distributor outside Mainland China: Springer 2007

Authors and Affiliations

  • Zhou Zhi-hua  (周智华)
    • 1
    • 2
  • Ruan Jian-ming  (阮建明)
    • 1
    Email author
  • Zou Jian-peng  (邹俭鹏)
    • 1
  • Zhou Zhong-cheng  (周忠诚)
    • 1
  • Shen Xiong-jun  (申雄军)
    • 1
  1. 1.State Key Laboratory of Powder MetallurgyCentral South UniversityChangshaChina
  2. 2.College of Chemistry and Chemical EngineeringHunan University of Science and TechnologyXiangtanChina

Personalised recommendations