Advertisement

Biocompatibility of MIM 316L stainless steel

  • Zhu Shai-hong Email author
  • Wang Guo-hui 
  • Zhao Yan-zhong 
  • Li Yi-ming 
  • Zhou Ke-chao 
  • Huang Bai-yun 
Materials Science and Engineering

Abstract

To evaluate the biocompatibility of MIM 316L stainless steel, the percentage of S-period cells were detected by flow cytometry after L929 incubated with extraction of MIM 316L stainless steel, using titanium implant materials of clinical application as the contrast. Both materials were implanted in animal and the histopathological evaluations were carried out. The statistical analyses show that there are no significant differences between two groups (P>0.05), which demonstrates that MIM 316L stainless steel has a good biocompatibility.

Key words

316L stainless steel metal powder injection moulding biocompatibility flow cytometry 

CLC number

TF764 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. [1]
    German R M. Technological barriers and opportunities in powder injection moulding[J]. Powder Metallurgy Int, 1993, 25(4): 165.Google Scholar
  2. [2]
    Merhar J R. Overview of metal injection moulding[J]. Metal Powder Report, 1990, 45(5): 339–342.CrossRefGoogle Scholar
  3. [3]
    Cacendish J C. Integrating feature-based surface design with freeform deformation[J]. Computer Aided Design, 1995, 27(9): 703–711.CrossRefGoogle Scholar
  4. [4]
    Walter M, Oliver P, Andreas F. Special injection moulding processes in practical application[J]. Kunststoffe Plast Europe, 2000, 90(10): 20–22.Google Scholar
  5. [5]
    Yu Y T, Zhang X D. Biomedical Materials[M]. Tianjin: Tianjin University Press, 2000. 28–34. (in Chinese)Google Scholar
  6. [6]
    Stivastava S, Stephen D G. Screening of in vitro cytoxicity by the adhesive test[J]. Biomaterial, 1990, 11(3): 133.CrossRefGoogle Scholar
  7. [7]
    Wang J Z, Wang S J. The tendency of development flow cytometry analyse at present [J]. Chin J Lab Med, 2002, 5(1): 5–7. (in Chinese)Google Scholar

Copyright information

© Central South University 2005

Authors and Affiliations

  • Zhu Shai-hong 
    • 1
    Email author
  • Wang Guo-hui 
    • 1
  • Zhao Yan-zhong 
    • 1
  • Li Yi-ming 
    • 2
  • Zhou Ke-chao 
    • 2
  • Huang Bai-yun 
    • 2
  1. 1.Transplantation Medical Academy, The Third Xiangya HospitalCentral South UniversityChangshaChina
  2. 2.State Key Laboratory of Powder MetallurgyCentral South UniversityChangshaChina

Personalised recommendations