Predictors of post-cancer diagnosis resignation among Japanese cancer survivors

  • Motoki EndoEmail author
  • Go Muto
  • Yuya Imai
  • Kiyomi Mitsui
  • Katsuji Nishimura
  • Kazuhiko Hayashi



In Japan, due to the increased incidence of cancer among the working population, it has become more important to support employees to achieve a balance between cancer treatment and work. This study aimed to clarify the predictors of resigning from employment after being diagnosed with cancer (post-cancer diagnosis [PCD] resignation) among Japanese employees.


As part of a Japanese national research project (Endo-Han), the investigators conducted a web-based survey of cancer survivors (CSs) in 2017. The investigators analyzed the risk factors for PCD resignation using a logistic regression model, including age at diagnosis, sex, cancer type, cancer stage, year of diagnosis, whether the patient held a managerial role, type of employment, and company size.


Of 750 employed Japanese CSs, 93 (12.4%) resigned from their jobs. The non-managers resigned more often (14.6%) than the managers (7.6%) (p = 0.007). The temporary workers exhibited the highest PCD resignation rates (22.2%), while the PCD resignation rates of the self-employed workers and permanent workers were 15.2% and 7.6%, respectively (p < 0.001). As the result of multivariate analysis, being female (odds ratio [OR], 3.67; 95%CI, 1.71–7.87), having hematological cancer (OR, 4.23; 95%CI, 1.37–13.04), having advanced cancer (OR, 2.48; 95%CI, 1.52–4.03), and being a temporary worker (OR, 2.51; 95%CI, 1.40–4.50) were identified as predictors of PCD resignation.


In total, 12.4% of Japanese employees quit their jobs after being diagnosed with cancer. Being female or a temporary worker and having advanced cancer were identified as predictors of PCD resignation. Regarding cancer type, hematological cancer was most strongly associated with PCD resignation.

Implication of Cancer Survivors

CSs who are females and temporary workers and have advanced cancer should be followed-up more carefully after cancer diagnosis for their work sustainability, by medical professionals, companies, and society.


Cancer survivors (CSs) Japanese employees Post-cancer diagnosis (PCD) resignation Cancer site Employment 


Funding information

This study was funded by grants from the Japanese Ministry of Health, Labour and Welfare (Research Grant: Gan-taisaku-ippan-012) to Motoki Endo. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Public HealthJuntendo University Faculty of MedicineTokyoJapan
  2. 2.Department of HygieneKitasato University School of MedicineTokyoJapan
  3. 3.Department of Hygiene, Public Health, and Preventive MedicineShowa UniversityTokyoJapan
  4. 4.Department of PsychiatryTokyo Women’s Medical University School of MedicineTokyoJapan
  5. 5.Department of Chemotherapy and Palliative CareTokyo Women’s Medical University HospitalTokyoJapan

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