Influenza vaccination in caregivers of childhood cancer survivors
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An increased risk of influenza-related morbidity and mortality in childhood cancer survivors could be significantly reduced through vaccinations. This study aimed to examine influenza vaccination practices by caregivers of childhood cancer survivors.
Study subjects were 364 caregivers, recruited at three major hospitals in South Korea. We collected demographic and medical information through self-administered questionnaires, along with clinical information of childhood cancer survivors by reviewing medical records. Multiple logistic regression analysis was performed to analyze factors associated with influenza vaccination of caregivers.
A total of 55.2% of caregivers had received influenza vaccination at least once and 24.2% had received yearly influenza vaccinations during the last 3 years. Caregivers with highest education level were more likely to receive influenza vaccination than caregivers with lowest education level: aOR (95% CI) was 3.42 (1.17, 9.99) for ever-receipt of vaccination and 3.33 (1.15, 9.58) for yearly vaccination. One-year increase in caregiver age was inversely associated with ever-receipt of vaccination (aOR (95% CI), 0.94 (0.90, 0.98)) as well as yearly vaccination (aOR (95% CI), 0.92 (0.88, 0.97)). Increasing time lapse since the end of treatment was also associated with lower vaccinations.
Influenza vaccination rates of childhood cancer survivor caregivers were suboptimal. Time lapse after completing cancer treatment, caregiver age, and educational level were independently associated with receipt of influenza vaccination by caregivers.
Implications for Cancer Survivors
To promote influenza vaccination in caregivers of childhood cancer survivors to prevent influenza-related morbidity and mortality in childhood cancer survivors is necessary.
KeywordsChildhood cancer survivor Caregiver Influenza Vaccination
This study was financially supported by a grant from the National Research and Development Program for Cancer Control, Ministry of Health & Welfare, Republic of Korea (1720270).
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of each institutional and/or national research committee (Samsung Medical Center IRB 2017-08-024, Seoul St. Mary’s Hospital IRB KC17ONDI0694, Chonnam National University Hwasun Hospital IRB CNUHH-2017-159) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
- 1.Korea Statistical Information Service. Pediatric cancer incidence rates according to international pediatric cancer classification. http://kosis.kr/statHtml/statHtml.do?orgId=117&tblId=DT_117N_A11105. Accessed July 10 2019.
- 6.Hudson SM, Newman SD, Hester WH, Magwood GS, Mueller M, Laken MA. Factors influencing hospital admissions and emergency department visits among children with complex chronic conditions: a qualitative study of parents’ and providers’ perspectives. Issues Compr Pediatr Nurs. 2014;37(1):61–80. https://doi.org/10.3109/01460862.2013.855844.CrossRefPubMedPubMedCentralGoogle Scholar
- 7.Bellizzi KM, Rowland JH, Jeffery DD, McNeel T. Health behaviors of cancer survivors: examining opportunities for cancer control intervention. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2005;23(34):8884–93. https://doi.org/10.1200/JCO.2005.02.2343.CrossRefGoogle Scholar
- 9.Oh MG, Han MA, Yun NR, Park J, Ryu SY, Kim DM, et al. A population-based, nationwide cross-sectional study on influenza vaccination status among cancer survivors in Korea. Int J Environ Res Public Health. 2015;12(8):10133–49. https://doi.org/10.3390/ijerph120810133.CrossRefPubMedPubMedCentralGoogle Scholar
- 13.Nair H, Brooks WA, Katz M, Roca A, Berkley JA, Madhi SA, et al. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. Lancet (London, England). 2011;378(9807):1917–30. https://doi.org/10.1016/S0140-6736(11)61051-9.CrossRefGoogle Scholar
- 16.Grohskopf LA, Sokolow LZ, Broder KR, Walter EB, Fry AM, Jernigan DB. (2018) Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices-United States, 2018-19 Influenza Season. MMWR Recommendations and reports : Morbidity and mortality weekly report Recommendations and reports. 67(3):1-20. https://doi.org/10.15585/mmwr.rr6703a1.CrossRefGoogle Scholar
- 18.Ortqvist A, Brytting M, Leval A, Hergens MP. Impact of repeated influenza vaccinations in persons over 65 years of age: a large population-based cohort study of severe influenza over six consecutive seasons, 2011/12-2016/17. Vaccine. 2018;36(37):5556–64. https://doi.org/10.1016/j.vaccine.2018.07.052.CrossRefPubMedGoogle Scholar
- 19.Korea Statistical Information Service. Trends in influenza vaccination rates for children and adolescents by sex and age (1-18 years) [in Korean]. 2019. http://kosis.kr/statHtml/statHtml.do?orgId=117&tblId=DT_11702_N084&vw_cd=MT_ZTITLE&list_id=117_11702_A01_077&seqNo=&lang_mode=ko&language=kor&obj_var_id=&itm_id=&conn_path=MT_ZTITLE. Accessed 6 Sept 2019.
- 22.Lee KC, Han K, Kim JY, Nam GE, Han BD, Shin KE, et al. Socioeconomic status and other related factors of seasonal influenza vaccination in the South Korean adult population based on a nationwide cross-sectional study. PloS one. 2015;10(2):e0117305. https://doi.org/10.1371/journal.pone.0117305.CrossRefPubMedPubMedCentralGoogle Scholar
- 23.Dyda A, MacIntyre CR, McIntyre P, Newall AT, Banks E, Kaldor J, et al. Factors associated with influenza vaccination in middle and older aged Australian adults according to eligibility for the national vaccination program. Vaccine. 2015;33(29):3299–305. https://doi.org/10.1016/j.vaccine.2015.05.046.CrossRefPubMedGoogle Scholar
- 24.Choi KH, Park SM, Lee K, Lee JH, Park JS. Influenza vaccination and associated factors among Korean cancer survivors: a cross-sectional analysis of the Fourth & Fifth Korea National Health and Nutrition Examination Surveys. J Korean Med Sci. 2014;29(8):1061–8. https://doi.org/10.3346/jkms.2014.29.8.1061.CrossRefPubMedPubMedCentralGoogle Scholar