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Benefits of partnered strength training for prostate cancer survivors and spouses: results from a randomized controlled trial of the Exercising Together project

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Abstract

Background

Prostate cancer can negatively impact quality of life of the patient and his spouse caregiver, but interventions rarely target the health of both partners simultaneously. We tested the feasibility and preliminary efficacy of a partnered strength training program on the physical and mental health of prostate cancer survivors (PCS) and spouse caregivers.

Methods

Sixty-four couples were randomly assigned to 6 months of partnered strength training (Exercising Together, N = 32) or usual care (UC, N = 32). Objective measures included body composition (lean, fat and trunk fat mass (kg), and % body fat) by DXA, upper and lower body muscle strength by 1-repetition maximum, and physical function by the physical performance battery (PPB). Self-reported measures included the physical and mental health summary scales and physical function and fatigue subscales of the SF-36 and physical activity with the CHAMPS questionnaire.

Results

Couple retention rates were 100 % for Exercising Together and 84 % for UC. Median attendance of couples to Exercising Together sessions was 75 %. Men in Exercising Together became stronger in the upper body (p < 0.01) and more physically active (p < 0.01) than UC. Women in Exercising Together increased muscle mass (p = 0.05) and improved upper (p < 0.01) and lower body (p < 0.01) strength and PPB scores (p = 0.01) more than UC.

Conclusions

Exercising Together is a novel couples-based approach to exercise that was feasible and improved several health outcomes for both PCS and their spouses.

Implications for cancer survivors

A couples-based approach should be considered in cancer survivorship programs so that outcomes can mutually benefit both partners.

Trial registration

ClinicalTrials.gov NCT00954044

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References

  1. American Cancer Society. Cancer Facts & Figures 2015. Atlanta: American Cancer Society; 2015.

    Google Scholar 

  2. Clay CA, Perera S, Wagner JM, Miller ME, Nelson JB, Greenspan SL. Physical function in men with prostate cancer on androgen deprivation therapy. Phys Ther. 2007;87(10):1325–33.

    Article  PubMed  Google Scholar 

  3. Sanda MG, Dunn RL, Michalski J, Sandler HM, Northouse L, Hembroff L, et al. Quality of life and satisfaction with outcome among prostate-cancer survivors. New Engl J Med. 2008;358(12):1250–61.

    Article  CAS  PubMed  Google Scholar 

  4. Smith MR, Saad F, Egerdie B, Sieber PR, Tammela TL, Ke C, et al. Sarcopenia during androgen-deprivation therapy for prostate cancer. J Clin Oncol. 2012;30(26):3271–6.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Rowland JH, Bellizzi KM. Cancer survivorship issues: life after treatment and implications for an aging population. J Clin Oncol. 2014;32(24):2662–8.

    Article  PubMed  PubMed Central  Google Scholar 

  6. U.S. Census Bureau. (2010). Families and Living Arrangements. Retrieved January 15, 2015 from https://www.census.gov/hhes/families/data/marital.html.

  7. Vitaliano PP, Zhang J, Scanlan JM. Is caregiving hazardous to one’s physical health? A meta-analysis. Psychol Bull. 2003;129(6):946–72.

    Article  PubMed  Google Scholar 

  8. Fredman L, Bertrand RM, Martire LM, Hochberg M, Harris EL. Leisure-time exercise and overall physical activity in older women caregivers and non-caregivers from the Caregiver-SOF Study. Prev Med. 2006;43(3):226–9.

    Article  PubMed  Google Scholar 

  9. Couper J, Bloch S, Love A, Macvean M, Duchesne GM, Kissane D. Psychosocial adjustment of female partners of men with prostate cancer: a review of the literature. Psychooncol. 2006;15(11):937–53.

    Article  Google Scholar 

  10. Lyons KS, Bennett JA, Nail LM, Fromme EK, Dieckmann N, Sayer AG. The role of patient pain and physical function on depressive symptoms in couples with lung cancer: a longitudinal dyadic analysis. J Fam Psychol. 2014;28(5):692–700.

    Article  PubMed  Google Scholar 

  11. Hagedoorn M, Sanderman R, Bolks HN, Tuinstra J, Coyne JC. Distress in couples coping with cancer: a meta-analysis and critical review of role and gender effects. Psychol Bull. 2008;134(1):1–30.

    Article  PubMed  Google Scholar 

  12. Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvao DA, Pinto BM, et al. American college of sports medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010;42(7):1409–26.

    Article  PubMed  Google Scholar 

  13. Gardner JR, Livingston PM, Fraser SF. Effects of exercise on treatment-related adverse effects for patients with prostate cancer receiving androgen-deprivation therapy: a systematic review. Journal of Clinical Oncology. 2014;32(4):335–46.

    Article  PubMed  Google Scholar 

  14. Castro CM, Wilcox S, O’Sullivan P, Baumann K, King AC. An exercise program for women who are caring for relatives with dementia. Psychosom Med. 2002;64(3):458–68.

    Article  PubMed  Google Scholar 

  15. Hong TB, Franks MM, Gonzalez R, Keteyian SJ, Franklin BA, Artinian NT. A dyadic investigation of exercise support between cardiac patients and their spouses. Health Psychol. 2005;24(4):430–4.

    Article  PubMed  Google Scholar 

  16. Winters-Stone KM, Dobek JC, Bennett JA, Maddalozzo GF, Ryan CW, Beer TM. Skeletal response to resistance and impact training in prostate cancer survivors. Med Sci Sports Exerc. 2014;46(8):1482–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Winters-Stone K, Dieckmann N, Maddalozzo GF, Bennett JA, Ryan CW, Beer TM. Resistance exercise reduces body fat and insulin during androgen deprivation therapy for prostate cancer. Oncol Nurs Forum. 2015;42(4):348–56.

    Article  PubMed  Google Scholar 

  18. Winters-Stone KM, Dobek JC, Bennett JA, Dieckmann NF, Maddalozzo GF, Ryan CW, et al. Resistance training reduces disability in prostate cancer survivors on androgen deprivation therapy: evidence from a randomized controlled trial. Arch Phys Med Rehab. 2015;96(1):7–14.

    Article  Google Scholar 

  19. Galvao DA, Spry N, Denham J, Taaffe DR, Cormie P, Joseph D, et al. A multicentre year-long randomised controlled trial of exercise training targeting physical functioning in men with prostate cancer previously treated with androgen suppression and radiation from TROG 03.04 RADAR. Eur Urol. 2014;65(5):856–64.

    Article  PubMed  Google Scholar 

  20. Segal RJ, Reid RD, Courneya KS, Sigal RJ, Kenny GP, Prud’Homme DG, et al. Randomized controlled trial of resistance or aerobic exercise in men receiving radiation therapy for prostate cancer. J Clin Oncol. 2009;27(3):344–51.

    Article  PubMed  Google Scholar 

  21. Schulz KF, Grimes DA. Sample size slippages in randomised trials: exclusions and the lost and wayward. Lancet. 2002;359(9308):781–5.

    Article  PubMed  Google Scholar 

  22. Winters-Stone KM, Dobek J, Bennett JA, Nail LM, Leo MC, Schwartz A. The effect of resistance training on muscle strength and physical function in older, postmenopausal breast cancer survivors: a randomized controlled trial. J Cancer Surviv. 2012;6(2):189–99.

    Article  PubMed  Google Scholar 

  23. Winters-Stone KM, Lyons KS, Nail LM, Beer TM. The Exercising Together project: design and recruitment for a randomized, controlled trial to determine the benefits of partnered strength training for couples coping with prostate cancer. Contemp Clin Trials. 2012;33(2):342–50.

    Article  PubMed  Google Scholar 

  24. Singh NA, Stavrinos TM, Scarbek Y, Galambos G, Liber C, Fiatarone Singh MA. A randomized controlled trial of high versus low intensity weight training versus general practitioner care for clinical depression in older adults. J Gerontol. 2005;60(6):768–76.

    Article  Google Scholar 

  25. Shaw JM, Snow CM. Weighted vest exercise improves indices of fall risk in older women. J Gerontol. 1998;53:M53–8.

    Article  CAS  Google Scholar 

  26. Winters-Stone K, Dobek J, Nail L, Bennett JA, Naik A, Schwartz A. Strength training stops bone loss and builds muscle in postmenopausal breast cancer survivors: a randomized controlled trial. Breast Cancer Res Treat. 2011;27(2):447–56.

    Article  Google Scholar 

  27. Winters-Stone KM, Dobek J, Nail LM, Bennett JA, Leo MC, Torgrimson-Ojerio B, et al. Impact + resistance training improves bone health and body composition in prematurely menopausal breast cancer survivors: a randomized controlled trial. Osteoporos Int. 2013;24(5):1637–46.

    Article  CAS  PubMed  Google Scholar 

  28. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.

    Article  CAS  PubMed  Google Scholar 

  29. American College of Sports Medicine. ACSM’s guildelines for exercise testing and prescription. 7th ed. ed. Philadelphia: Lippincott Williams & Wilkins; 2006.

  30. Guralnik J, Simonsick E, Ferrucci L, Glynn R, Berkman L, Blazer D, et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49(2):M85–94.

    Article  CAS  PubMed  Google Scholar 

  31. Perera S, Mody SH, Woodman RC, Studenski SA. Meaningful change and responsiveness in common physical performance measures in older adults. Journal of the American Geriatrics Society. 2006;54(5):743–9.

    Article  PubMed  Google Scholar 

  32. Ware Jr JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30(6):473–83.

    Article  PubMed  Google Scholar 

  33. Hopman WM, Towheed T, Anastassiades T, Tenenhouse A, Poliquin S, Berger C, et al. Canadian normative data for the SF-36 health survey. J Can Med Assoc. 2000;163(3):265–71.

    CAS  Google Scholar 

  34. Stewart A, Mills K, King A, Haskell W, Gillis D, Ritter P. CHAMPS physical activity questionnaire for older adults: outcomes for interventions. Med Sci Sports Exerc. 2001;33(7):1126–41.

    Article  CAS  PubMed  Google Scholar 

  35. Ottenbacher A, Yu M, Moser RP, Phillips SM, Alfano C, Perna FM. Population estimates of meeting strength training and aerobic guidelines, by gender and cancer survivorship status: findings from the Health Information National Trends Survey (HINTS). J Phys Act Health. 2015;12(5):675–9.

  36. Demark-Wahnefried W, Jones LW, Snyder DC, Sloane RJ, Kimmick GG, Hughes DC, et al. Daughters and Mothers Against Breast Cancer (DAMES): main outcomes of a randomized controlled trial of weight loss in overweight mothers with breast cancer and their overweight daughters. Cancer. 2014;120(16):2522–34.

    Article  PubMed  Google Scholar 

  37. Galvao DA, Taaffe DR, Spry N, Joseph D, Newton RU. Combined resistance and aerobic exercise program reverses muscle loss in men undergoing androgen suppression therapy for prostate cancer without bone metastases: a randomized controlled trial. J Clin Oncol. 2010;28(2):340–7.

    Article  CAS  PubMed  Google Scholar 

  38. Cormie P, Galvao DA, Spry N, Joseph D, Chee R, Taaffe DR, et al. Can supervised exercise prevent treatment toxicity in prostate cancer patients initiating androgen deprivation therapy: a randomised controlled trial. BJU Int. 2014;115(2):256–66.

    Article  PubMed  Google Scholar 

  39. Parsons J Prostate cancer and the therapeutic benefits of structured exercise. J Clin Oncol. 2014;32(4):271–2.

    Article  PubMed  Google Scholar 

  40. Jackson SE, Steptoe A, Wardle J. The influence of partner’s behavior on health behavior change: the English longitudinal study of ageing. JAMA Internal Medicine. 2015;175(3):385–92.

    Article  PubMed  Google Scholar 

  41. Coyne JC, Smith DA. Couples coping with a myocardial infarction: a contextual perspective on wives’ distress. J Personal Soc Psychol. 1991;61:404–12.

    Article  CAS  Google Scholar 

  42. Perera S, Mody SH, Woodman RC, Studensk SA. Meaningful change and responsiveness in common physical performance measures in older adults. J Am Geriatr Soc. 2006;54(5):743–9.

    Article  PubMed  Google Scholar 

  43. Zhou ES, Kim Y, Rasheed M, Benedict C, Bustillo NE, Soloway M, et al. Marital satisfaction of advanced prostate cancer survivors and their spousal caregivers: the dyadic effects of physical and mental health. Psychooncol. 2011;20(12):1353–7.

    Article  Google Scholar 

  44. Winters-Stone KM, Neil SE, Campbell KL. Attention to principles of exercise training: a review of exercise studies for survivors of cancers other than breast. Br J Sports Med. 2014;48(12):987–95.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Knight Cancer Institute, Oregon Health and Science University, Portland, OR, 97239, USA

    Kerri M. Winters-Stone, Karen S. Lyons, Jill A. Bennett, Lillian Nail & Tomasz M. Beer

  2. School of Nursing, Oregon Health and Science University, Portland, OR, 97239, USA

    Kerri M. Winters-Stone, Karen S. Lyons, Jessica Dobek, Nathan F. Dieckmann, Jill A. Bennett & Lillian Nail

Authors
  1. Kerri M. Winters-Stone
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  2. Karen S. Lyons
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  3. Jessica Dobek
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  5. Jill A. Bennett
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Corresponding author

Correspondence to Kerri M. Winters-Stone.

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The authors have no conflicts to report.

Funding source

This study was funded by the National Institutes of Health 1R21 CA137272.

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Winters-Stone, K.M., Lyons, K.S., Dobek, J. et al. Benefits of partnered strength training for prostate cancer survivors and spouses: results from a randomized controlled trial of the Exercising Together project. J Cancer Surviv 10, 633–644 (2016). https://doi.org/10.1007/s11764-015-0509-0

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  • DOI: https://doi.org/10.1007/s11764-015-0509-0

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