Cancer research network: using integrated healthcare delivery systems as platforms for cancer survivorship research
Much progress has been made in cancer survivorship research, but there are still many unanswered questions that can and need to be addressed by collaborative research consortia.
Since 1999, the National Cancer Institute-funded HMO Cancer Research Network (CRN) has engaged in a wide variety of research focusing on cancer survivorship. With a focus on thematic topics in cancer survivorship, we describe how the CRN has contributed to research in cancer survivorship and the resources it offers for future collaborations.
We identified the following areas of cancer survivorship research: surveillance for and predictors of recurrences, health care delivery and care coordination, health care utilization and costs, psychosocial outcomes, cancer communication and decision making, late effects of cancer and its treatment, use of and adherence to adjuvant therapies, and lifestyle and behavioral interventions following cancer treatment.
With over a decade of experience using cancer data in community-based settings, the CRN investigators and their collaborators are poised to generate evidence in cancer survivorship research.
Implications for Cancer Survivors
Collaborative research within these settings can improve the quality of care for cancer survivors within and beyond integrated health care delivery systems.
KeywordsCancer survivorship Integrated health care systems Heath services research
- 1.Institute of Medicine and National Research Council of the National Academies. From cancer patient to cancer survivor: lost in transition. Washington: The National Academies Press; 2006.Google Scholar
- 5.The HMO Cancer Research Network: Capacity, Collaboration, and Investigation. http://crncancergov/publications/capacity_collaboration_investigation_2010_aprpdf2011 [accessed 2012 Mar 19].
- 8.Ritzwoller DP, Carroll N, Delate T, O’Keeffe-Rossetti M, Fishman PA, Loggers ET, et al. Validation of electronic data on chemotherapy use in HMOs. Med Care. 2012. doi:10.1097/MLR.0b013e31824def85.
- 15.Specimen collection within the CRN: a critical appraisal. http://crncancergov/publications/crn_specimen_collectionpdf2010 [accessed 2012 Mar 19].
- 25.Salloum RG, Hornbrook MC, Fishman PA, Ritzwoller DP, O’Keeffe-Rossetti M, Elston-Lafata J. Adherence to surveillance care guidelines after breast and colorectal cancer treatment with curative intent. Cancer. 2012;118(22):5644–51.Google Scholar
- 26.Sox HC, Greenfield S. Comparative effectiveness research: a report from the Institute of Medicine. Annals Intern Med. 2009;151:203–5.Google Scholar
- 36.Rowland JH, Mariotto A, Alfano CM, Pollack LA, Weir HK, White A. Cancer survivors—United States, 2007. MMMR. 2011;60:26–272.Google Scholar
- 37.The Kaiser Family Foundation. State Health Facts. http://www.statehealthfactsorg/comparebarjsp?ind=349&cat=7&sub=85&yr=194&typ=2&sort=a2011 [accessed 2012 Mar 19].
- 38.A National Coalition for Cancer Survivorship and Institute of Medicine National Cancer Policy Forum Workshop TLAFaTNCI. Implementing Cancer Survivorship Care Planning. Washington, D.C.: The National Academies Press; 2007.Google Scholar
- 47.Lux MP, Wöckel A, Benedict A, Buchholz S, Kreif N, et al. Cost-effectiveness analysis of anastrozole versus tamoxifen in adjuvant therapy for early-stage breast cancer—a health-economic analysis based on the 100-month analysis of the ATAC trial and the German health system. Onkologie. 2010;33:155–66.PubMedCrossRefGoogle Scholar
- 49.Committee on Psychosocial Services to Cancer Patients/Families in a Community Setting. Cancer care for the whole patient: meeting psychosocial health needs. Washington: The National Academies Press; 2008.Google Scholar
- 58.Mazor KM, Roblin DW, Greene SM, Lemay CA, Firneno CL, Calvi J, et al. Toward patient-centered cancer care: patient perceptions of problematic events, impact, and response. J Clin Oncol 2012. J Clin Oncol 2012;Apr 16 [Epub ahead of print].Google Scholar
- 59.Mazor KM, Greene SM, Roblin D, Lemay CA, Firneno CL, Calvi J, et al. More than words: patients’ views on apology and disclosure when things go wrong in cancer care. Patient Educ Couns. 2011. doi:10.1016/j.pec.2011.07.010.
- 62.Epstein RM, Street RL, Jr. Patient-centered communication in cancer care: Promoting healing and reducing suffering. National Cancer Institute 2007;No. 07-6225.Google Scholar
- 63.Aiello Bowles EJ, Wellman R, Feigelson HS, Onitilo AA, Freedman AN, Delate T, et al. Risk of heart failure in breast cancer patients after anthracycline and trastuzumab treatment: a retrospective cohort study. J Natl Cancer Inst. 2012;104:1293–305.Google Scholar