Quality assessment using EQ-5D-5L after lung surgery for non-small cell lung cancer (NSCLC) patients
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Aim of this study was to elucidate an alteration of quality of life (QOL) score before and after video-assisted thoracoscopic surgery (VATS) for non-small cell lung cancer (NSCLC) patients using the 5-level EuroQol-5D questionnaire (EQ-5D-5L). We also investigated how the preoperative QOL scores affected the postoperative clinical outcome prospectively.
Between July 2018 and December 2018, 24 consecutive NSCLC patients who underwent VATS were recruited. The EQ-5D-5L for Japanese was used with face-to-face interviews to estimate the utility values of QOL.
QOL scores were significantly declined after surgery (0.81 ± 0.19 vs. 0.74 ± 0.11: P = 0.049). The levels of EQ-5D-5L questionnaire were not significantly different before and after surgery except Q4 (pain control). The levels of Q4 were significantly worsened after surgery (1.33 ± 0.56 vs. 1.88 ± 0.61, P < 0.001). Operation time and bleeding in the preoperative low-QOL score group (N = 13) was longer (215.4 ± 52.3 min. vs. 173.5 ± 42.3 min., respectively: P = 0.045) and more (116.2 ± 152.7 ml vs. 22.7 ± 20.1 ml, respectively: P = 0.049) than those in the high-QOL score group (N = 11).
QOL survey for lung cancer patients using EQ-5D-5L is simple and useful to identify the issue facing at the medical team. Preoperative low QOL score could be a predicting factor for the longer operation time and more bleeding.
KeywordsLung surgery EuroQol Pain Quality of life VATS
Supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan, no. 17K10672 to T. Mizuguchi. Part of the study was also supported by Astellas Pharma Inc. (Tokyo, Japan), Daiichi Sankyo Company (Tokyo, Japan), Shionogi & Co. (Osaka, Japan), Sapporo Doto Hospital (Sapporo, Japan), Noguchi Hospital (Otaru, Japan), Doki-kai Tomakomai Hospital (Tomakomai, Japan), Tsuchida Hospital (Sapporo, Japan) and Ikuta Hospital (Shiraoi, Japan).
Compliance with ethical standards
Conflict of interest
Ryo Koide and other co-authors have no conflict of interest.
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